Singulair and Biktarvy drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Singulair (montelukast sodium) and Biktarvy (bictegravir sodium; emtricitabine; tenofovir alafenamide fumarate). Common drug interactions include lower limb fracture among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Singulair and Biktarvy. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Biktarvy?

Biktarvy has active ingredients of bictegravir sodium; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 19,543 Biktarvy users. Check the latest studies of Biktarvy.

On Jul, 08, 2026

56 people who take Singulair and Biktarvy together, and have interactions are studied.

Singulair and Biktarvy drug interactions.

What are the common drug interactions of Singulair and Biktarvy, by gender? *:

female:

Lower limb fracture
Neck pain
Osteomalacia (softening of the bones due to a lack of vitamin d)
Pain in extremity
Proteinuria (presence of protein in the urine)
Renal failure (kidney dysfunction)
Alopecia (absence of hair from areas of the body)
Bone disorder
Cervical vertebral fracture
Death

male:

Emotional distress
Pain
Loss of consciousness
Mastoiditis (infection of mastoid bone)
Multiple fractures
Osteonecrosis (death of bone)
Renal impairment (severely reduced kidney function)
Foot fracture
Hand fracture
Osteopenia (a condition where bone mineral density is lower than normal)

What are the common drug interactions of Singulair and Biktarvy, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Alopecia (absence of hair from areas of the body)
Anal abscess
Impetigo (contagious skin infection)
Nausea (feeling of having an urge to vomit)
Sleep disorder

30-39:

Osteoporosis (bones weak and more likely to break)
Proteinuria (presence of protein in the urine)
Bone density decreased
Emotional distress
Pain
Depression
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Bone loss

40-49:

n/a

50-59:

Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Osteopenia (a condition where bone mineral density is lower than normal)
Chronic kidney disease
Multiple fractures
Osteoporosis (bones weak and more likely to break)
Bone density decreased
Depression

60+:

Arthralgia (joint pain)
Pruritus (severe itching of the skin)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Speech disorder
Adverse event
Balance disorder
Confusional state
Diarrhoea
Dizziness
Fear

What are the existing conditions these people have? *

Depression: 10 people, 17.86%
Insomnia (sleeplessness): 10 people, 17.86%
High Blood Pressure: 9 people, 16.07%
Irritable Bowel Syndrome: 7 people, 12.50%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 12.50%
Psoriasis (immune-mediated disease that affects the skin): 6 people, 10.71%
High Blood Cholesterol: 6 people, 10.71%
Pain: 6 people, 10.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 10.71%
Fungal Infection: 6 people, 10.71%

* Approximation only. Some reports may have incomplete information.

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