Singulair and Dynacirc drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Singulair (montelukast sodium) and Dynacirc (isradipine). Common drug interactions include dyspnoea among females and back pain among males.
The phase IV clinical study analyzes what interactions people have when they take Singulair and Dynacirc. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Singulair?
Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.
What is Dynacirc?
Dynacirc has active ingredients of isradipine. eHealthMe is studying from 975 Dynacirc users. Check the latest studies of Dynacirc.
20 people who take Singulair and Dynacirc together, and have interactions are studied.

What are the common drug interactions of Singulair and Dynacirc, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Muscular weakness (muscle weakness)
- Abdominal pain
- Aphasia (damage to the parts of the brain that control language)
- Blood creatinine increased
- Blood potassium increased
- Blood pressure decreased
- Blood urea increased
- Bradycardia (abnormally slow heart action)
male:
- Back pain
- Disease progression
- Antinuclear antibody positive
- Blood pressure increased
- Cardiovascular disorder (heart diseases)
- Diarrhoea
- Gastrointestinal arteriovenous malformation (malformation of arteries and veins in gastrointestinal tract)
- Haematochezia (passage of stools containing blood)
- Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
- Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
What are the common drug interactions of Singulair and Dynacirc, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Back pain
- Disease progression
60+:
- Dyspnoea (difficult or laboured respiration)
- Abdominal pain
- Hypotension (abnormally low blood pressure)
- Hypovolaemic shock (shock caused by severe blood or fluid loss)
- Injection site haemorrhage (bleeding from injection site)
- Muscle haemorrhage (bleeding in muscle)
- Myoglobin blood increased (presence of myoglobin in blood increased)
- Pallor
- Rash
- Renal failure (kidney dysfunction)
What are the existing conditions these people have? *
- Lung Carcinoma Cell Type Unspecified Stage 0 (the lung cancer has not spread beyond the inner lining of the lung): 2 people, 10.00%
- Lung Cancer - Non-Small Cell (lung cancer): 2 people, 10.00%
- High Blood Pressure: 2 people, 10.00%
- Heart Attack: 2 people, 10.00%
- Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 2 people, 10.00%
- Respiratory Tract Infection Bacterial: 1 person, 5.00%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Singulair and Dynacirc?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Singulair and Dynacirc:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Singulair:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dynacirc:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Singulair and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dynacirc and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on montelukast sodium and isradipine (the active ingredients of Singulair and Dynacirc, respectively), and Singulair and Dynacirc (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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