Singulair and Grape drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Singulair (montelukast sodium) and Grape (grape). Common drug interactions include myalgia among females and decreased immune responsiveness among males.

The phase IV clinical study analyzes what interactions people have when they take Singulair and Grape. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Grape?

Grape has active ingredients of grape. eHealthMe is studying from 1,229 Grape users. Check the latest studies of Grape.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

55 people who take Singulair and Grape together, and have interactions are studied.

What are the common drug interactions of Singulair and Grape, by gender? *:

female:

Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Oral disorder (mouth disease)
Pneumonia
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash macular (small, flat red spots)
Rash vesicular (rash with a small bubble)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Sneezing

male:

Decreased immune responsiveness
Addison's disease (addison's disease, a hormonal disorder disease)
Pain in jaw
Blood glucose increased
Blood pressure fluctuation
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)
Chills (felling of cold)
Diarrhoea
Drug hypersensitivity

What are the common drug interactions of Singulair and Grape, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Chills (felling of cold)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Infusion related reaction
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Overdose
Oxygen saturation decreased

20-29:

n/a

30-39:

Dyspnoea (difficult or laboured respiration)
Wheezing (a high-pitched whistling sound made while you breath)
Anaphylactic reaction (serious allergic reaction)
Chest discomfort
Cough
Facial pain
Pulmonary function test decreased
Rhinorrhoea (watery mucus discharge from the nose)
Weight decreased

40-49:

Menopause (end of monthly cycles in women)
Menstruation irregular
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Vulvovaginal mycotic infection (vulvovaginal fungal infection)

50-59:

Addison's disease (addison's disease, a hormonal disorder disease)
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Osteoporosis (bones weak and more likely to break)
Pruritus (severe itching of the skin)
Rhinorrhoea (watery mucus discharge from the nose)
Arthralgia (joint pain)
Blood pressure fluctuation
Cataract (clouding of the lens inside the eye)
Decreased immune responsiveness

60+:

Body height decreased
Cough
Throat irritation
Blood glucose increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Disability
Dizziness
Gastric disorder (disease of stomach)
Headache (pain in head)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 34.55%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 16.36%
Immunodeficiency: 8 people, 14.55%
Immunodeficiency Common Variable: 7 people, 12.73%
Depression: 7 people, 12.73%
Multiple Myeloma (cancer of the plasma cells): 5 people, 9.09%
Primary Immunodeficiency Syndrome: 3 people, 5.45%
High Blood Cholesterol: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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