Singulair and Questran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Singulair (montelukast sodium) and Questran (cholestyramine). Common drug interactions include paraesthesia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Singulair and Questran. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.

On Jul, 10, 2026

98 people who take Singulair and Questran together, and have interactions are studied.

Singulair and Questran drug interactions.

What are the common drug interactions of Singulair and Questran, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash
Vomiting
Weight decreased
Paranasal sinus hypersecretion
Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
Chest pain
Cystitis (inflammation of the wall of the bladder)

male:

Drug ineffective
Blood creatine phosphokinase increased
Urinary tract infection
Blood sodium decreased
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Cough
Haemoglobin decreased
Influenza like illness
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)

What are the common drug interactions of Singulair and Questran, by age (0-1 to 60+)? *:

0-1:

Lymphopenia (an abnormally low level of lymphocytes in the blood)

2-9:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Low birth weight baby
Premature baby

10-19:

Petit mal epilepsy (absence seizure)
Syncope (loss of consciousness with an inability to maintain postural tone)

20-29:

Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)

30-39:

Abdominal pain
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Colonic obstruction (obstruction in colon)
Colonic stenosis (abnormal narrowing of colon)
Constipation
Dissociation
Inflammation
Mucosal erosion (peeling off of mucous membrane)
Mucosal ulceration (ulcers of mucous membrane)
Pelvic peritoneal adhesions

40-49:

Drug ineffective
Pyrexia (fever)
Abdominal pain
Alanine aminotransferase increased
Arthralgia (joint pain)
Aspartate aminotransferase increased
Autoimmune thrombocytopenia (isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Chills (felling of cold)

50-59:

Asthenia (weakness)
Blood creatine phosphokinase increased
Blood triglycerides increased
Chest discomfort
Chest pain
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug ineffective
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)

60+:

Headache (pain in head)
Sinusitis (inflammation of sinus)
Death
Drug ineffective
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Respiratory tract infection
Septic shock (shock due to blood infection)
Upper respiratory tract infection
Blood sodium decreased

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 22 people, 22.45%
High Blood Pressure: 19 people, 19.39%
Pain: 15 people, 15.31%
Hypersensitivity: 14 people, 14.29%
Stress And Anxiety: 12 people, 12.24%
Nausea (feeling of having an urge to vomit): 11 people, 11.22%
Depression: 10 people, 10.20%
High Blood Cholesterol: 8 people, 8.16%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 8.16%
Seasonal Allergy (allergic condition due to certain season): 7 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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