Singulair and Tapazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Singulair (montelukast sodium) and Tapazole (methimazole). Common drug interactions include bone disorder among females.

The phase IV clinical study analyzes what interactions people have when they take Singulair and Tapazole. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Tapazole?

Tapazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 2,477 Tapazole users. Check the latest studies of Tapazole.

On Jul, 10, 2026

72 people who take Singulair and Tapazole together, and have interactions are studied.

Singulair and Tapazole drug interactions.

What are the common drug interactions of Singulair and Tapazole, by gender? *:

female:

Bone disorder
Weight decreased
Dyspnoea (difficult or laboured respiration)
Fall
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Cellulitis (infection under the skin)
Gait disturbance
Anxiety
Asthenia (weakness)

male:

n/a

What are the common drug interactions of Singulair and Tapazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Ageusia (loss of taste functions of the tongue)
Anosmia (partial or complete loss of the sense of smell)
Anaphylactic reaction (serious allergic reaction)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Hunger
Hypotension (abnormally low blood pressure)
Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Mitral valve incompetence (inefficient heart valve)
Oedema peripheral (superficial swelling)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Productive cough
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Tricuspid valve incompetence (inefficient heart valve)
Abdominal discomfort
Abdominal distension
Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)

50-59:

Burning sensation
Rash pruritic (redness with itching)

60+:

Bone disorder
Swelling
Fall
Fatigue (feeling of tiredness)
Bronchial secretion retention
Cellulitis (infection under the skin)
Gait disturbance
Muscle atrophy (a decrease in the mass of the muscle)
Nausea (feeling of having an urge to vomit)
Accident

What are the existing conditions these people have? *

High Blood Pressure: 30 people, 41.67%
Hypersensitivity: 27 people, 37.50%
Thyroid Diseases: 26 people, 36.11%
Productive Cough: 25 people, 34.72%
Bronchopulmonary Aspergillosis Allergic (allergic lung disorder caused by aspergillus fungi): 25 people, 34.72%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 25 people, 34.72%
Blood Immunoglobulin E Increased: 25 people, 34.72%
Depression: 23 people, 31.94%
Stress And Anxiety: 19 people, 26.39%
Sputum Discolored: 18 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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