Singulair and Tepezza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Singulair (montelukast sodium) and Tepezza (teprotumumab-trbw). Common drug interactions include eyelids pruritus among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Singulair and Tepezza. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Tepezza?

Tepezza has active ingredients of teprotumumab-trbw. eHealthMe is studying from 3,632 Tepezza users. Check the latest studies of Tepezza.



On Jul, 17, 2026

13 people who take Singulair and Tepezza together, and have interactions are studied.

Singulair and Tepezza drug interactions.

What are the common drug interactions of Singulair and Tepezza, by gender? *:

female:

  1. Eyelids pruritus (eyelids itching)
  2. Pruritus (severe itching of the skin)
  3. Swelling face
  4. Deafness

male:

  1. Fatigue (feeling of tiredness)

What are the common drug interactions of Singulair and Tepezza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Fatigue (feeling of tiredness)

60+:

  1. Deafness

What are the existing conditions these people have? *

  1. Endocrine Ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism): 12 people, 92.31%
  2. Nausea (feeling of having an urge to vomit): 2 people, 15.38%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
  4. High Blood Cholesterol: 1 person, 7.69%
  5. Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Singulair and Tepezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Singulair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tepezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Singulair and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tepezza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on montelukast sodium and teprotumumab-trbw (the active ingredients of Singulair and Tepezza, respectively), and Singulair and Tepezza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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