Sirolimus and Atarax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sirolimus (sirolimus) and Atarax (hydroxyzine hydrochloride). Common drug interactions include death among females and liver transplant rejection among males.

The phase IV clinical study analyzes what interactions people have when they take Sirolimus and Atarax. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

On Jul, 11, 2026

18 people who take Sirolimus and Atarax together, and have interactions are studied.

What are the common drug interactions of Sirolimus and Atarax, by gender? *:

female:

Death
Aplasia (defective development or congenital absence of an organ or tissue)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Respiratory distress (difficulty in breathing)
Viral infection
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Renal failure (kidney dysfunction)

male:

Liver transplant rejection (failure of liver transplant)
Abdominal pain upper
Cholangitis (infection of the bile duct)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Thrombosis (formation of a blood clot inside a blood vessel)
Upper respiratory tract infection
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Cough
Dyspnoea (difficult or laboured respiration)
Blood creatinine increased

What are the common drug interactions of Sirolimus and Atarax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aplasia (defective development or congenital absence of an organ or tissue)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Respiratory distress (difficulty in breathing)
Viral infection

20-29:

Liver transplant rejection (failure of liver transplant)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Blood creatinine increased

30-39:

n/a

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

n/a

60+:

Death

What are the existing conditions these people have? *

Hyperglycemia (high blood sugar): 2 people, 11.11%
Thrombocytopenia (decrease of platelets in blood): 2 people, 11.11%
Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 2 people, 11.11%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 11.11%
Pain: 2 people, 11.11%
High Blood Pressure: 2 people, 11.11%
Urinary Tract Infection: 2 people, 11.11%
Itching: 2 people, 11.11%
Hypertensive Crisis: 2 people, 11.11%
Weakness: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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