Sitagliptin and Bactrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sitagliptin (sitagliptin) and Bactrim (sulfamethoxazole; trimethoprim). Common drug interactions include asthenia among females and leukopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Sitagliptin and Bactrim. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Sitagliptin?

Sitagliptin has active ingredients of sitagliptin. eHealthMe is studying from 3,933 Sitagliptin users. Check the latest studies of Sitagliptin.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

On Jul, 20, 2026

33 people who take Sitagliptin and Bactrim together, and have interactions are studied.

Sitagliptin and Bactrim drug interactions.

What are the common drug interactions of Sitagliptin and Bactrim, by gender? *:

female:

Asthenia (weakness)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Anaemia (lack of blood)
Dyspnoea exertional (breathlessness or shortness of breath)
Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)

male:

Leukopenia (less number of white blood cells in blood)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Constipation
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Foot fracture
Hyperkalaemia (damage to or disease of the kidney)
Malaise (a feeling of general discomfort or uneasiness)
Mixed liver injury

What are the common drug interactions of Sitagliptin and Bactrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Foot fracture

40-49:

Mixed liver injury

50-59:

Leukopenia (less number of white blood cells in blood)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Neutropenia (an abnormally low number of neutrophils)
Acute respiratory distress syndrome
Pneumonia

60+:

Asthenia (weakness)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Restless legs syndrome (a powerful urge to move your legs)
Septic shock (shock due to blood infection)
Thrombocytopenia (decrease of platelets in blood)
Aplasia (defective development or congenital absence of an organ or tissue)
Escherichia sepsis (bacterial infection by escherichia coli)
Abdominal pain
Bone marrow failure
Constipation

What are the existing conditions these people have? *

Pain: 14 people, 42.42%
Dyslipidaemia (abnormal amount of lipids): 14 people, 42.42%
Hiv Test Positive: 12 people, 36.36%
Breast Cancer Male: 12 people, 36.36%
Diabetes: 12 people, 36.36%
Itching: 10 people, 30.30%
Multiple Myeloma (cancer of the plasma cells): 6 people, 18.18%
High Blood Pressure: 5 people, 15.15%
Burkitt Lymphoma (cancer of the lymphatic system): 4 people, 12.12%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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