Sitagliptin and Insulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sitagliptin (sitagliptin) and Insulin (insulin pork). Common drug interactions include diarrhoea among females and blood pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Sitagliptin and Insulin. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Sitagliptin?

Sitagliptin has active ingredients of sitagliptin. eHealthMe is studying from 3,933 Sitagliptin users. Check the latest studies of Sitagliptin.

What is Insulin?

Insulin has active ingredients of insulin pork. It is often used in diabetes. eHealthMe is studying from 50,203 Insulin users. Check the latest studies of Insulin.

On Jul, 06, 2026

46 people who take Sitagliptin and Insulin together, and have interactions are studied.

Sitagliptin and Insulin drug interactions.

What are the common drug interactions of Sitagliptin and Insulin, by gender? *:

female:

Diarrhoea
Autoimmune hepatitis
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Hyperglycaemia (high blood sugar)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Nausea (feeling of having an urge to vomit)
Neuromyopathy (disease of both muscles and nerves)
Oesophageal candidiasis (fungal infection of oesophagus)
Urinary tract infection

male:

Blood pressure increased
Infusion related reaction
Fatigue (feeling of tiredness)
Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
Hypotension (abnormally low blood pressure)
Loss of consciousness
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Pleural effusion (water on the lungs)
Renal cyst (kidney cyst)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the common drug interactions of Sitagliptin and Insulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cytomegalovirus oesophagitis (oesophagus infection with cytomegalo virus)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

50-59:

Diarrhoea
Autoimmune hepatitis
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Oesophageal candidiasis (fungal infection of oesophagus)
Blood pressure fluctuation
Blood pressure increased
Blood urine present
Body temperature increased
Bone erosion

60+:

Fall
Hypotension (abnormally low blood pressure)
Diarrhoea
Syncope (loss of consciousness with an inability to maintain postural tone)
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Fatigue (feeling of tiredness)
Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
Loss of consciousness
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the existing conditions these people have? *

Type 2 Diabetes: 12 people, 26.09%
Vasculitis (inflammation of a blood vessel or blood vessels): 8 people, 17.39%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 13.04%
Antisynthetase Syndrome (chronic autoimmune disease of unknown cause): 6 people, 13.04%
High Blood Pressure: 5 people, 10.87%
Pain: 4 people, 8.70%
Dyslipidaemia (abnormal amount of lipids): 4 people, 8.70%
Chronic Kidney Disease: 4 people, 8.70%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 8.70%
Urinary Tract Infection: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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