Slow-k and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Slow-k (potassium chloride) and Codeine (codeine sulfate). Common drug interactions include nausea among females and tachycardia among males.

The phase IV clinical study analyzes what interactions people have when they take Slow-k and Codeine. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Slow-k?

Slow-k has active ingredients of potassium chloride. It is often used in hypokalemia. eHealthMe is studying from 3,683 Slow-k users. Check the latest studies of Slow-k.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.



On Jul, 03, 2026

26 people who take Slow-k and Codeine together, and have interactions are studied.

Slow-k and Codeine drug interactions.

What are the common drug interactions of Slow-K and Codeine, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Haemoglobin decreased
  3. International normalised ratio increased
  4. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  5. Abdominal discomfort
  6. Activated partial thromboplastin time prolonged
  7. Arthralgia (joint pain)
  8. Arthrodesis
  9. Body temperature increased
  10. Catheter site infection (infection at the site of insertion)

male:

  1. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  2. Blood potassium decreased
  3. C-reactive protein increased
  4. Chest discomfort
  5. Decreased appetite
  6. Infection
  7. Pneumonia
  8. Appendicitis (inflammation of the appendix)
  9. Blood pressure decreased
  10. Drug dependence

What are the common drug interactions of Slow-K and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Appendicitis (inflammation of the appendix)
  2. Blood pressure decreased
  3. C-reactive protein increased
  4. Drug dependence
  5. Drug level below therapeutic
  6. Fatigue (feeling of tiredness)
  7. Feeling cold
  8. Headache (pain in head)
  9. Heart rate increased
  10. Heart rate irregular

20-29:

n/a

30-39:

  1. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  2. Activated partial thromboplastin time prolonged
  3. Disease progression
  4. General physical health deterioration (weak health status)
  5. Haemoglobin decreased
  6. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  7. Haemorrhage (bleeding)
  8. Platelet count decreased
  9. Red blood cell count decreased

40-49:

  1. Multi-organ failure (multisystem organ failure)

50-59:

  1. Arthrodesis
  2. Drug ineffective
  3. Eye infection toxoplasmal (a germ called toxoplasma can cause infection within the eye)
  4. Localised infection (infection at the single location)
  5. Uveitis (inflammation of the uvea)

60+:

  1. Cough
  2. Dyspnoea (difficult or laboured respiration)
  3. Oesophageal fistula (a birth defect, with the trachea connected to the oesophagus)
  4. Pneumonia
  5. Infection
  6. International normalised ratio increased
  7. Pyrexia (fever)
  8. Abdominal discomfort
  9. Arthralgia (joint pain)
  10. Body temperature increased

What are the existing conditions these people have? *

  1. High Blood Pressure: 6 people, 23.08%
  2. Lung Cancer - Non-Small Cell (lung cancer): 5 people, 19.23%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 19.23%
  4. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 11.54%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 11.54%
  6. Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 11.54%
  7. Cough: 3 people, 11.54%
  8. Diarrhea: 3 people, 11.54%
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 3 people, 11.54%
  10. Type 2 Diabetes: 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you take Slow-k and Codeine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Slow-k and Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Slow-k:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Slow-k and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Codeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on potassium chloride and codeine sulfate (the active ingredients of Slow-k and Codeine, respectively), and Slow-k and Codeine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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