Slynd and Cymbalta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Slynd (drospirenone) and Cymbalta (duloxetine hydrochloride). Common drug interactions include hypersensitivity among females.

The phase IV clinical study analyzes what interactions people have when they take Slynd and Cymbalta. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Slynd?

Slynd has active ingredients of drospirenone. It is often used in birth control. eHealthMe is studying from 1,658 Slynd users. Check the latest studies of Slynd.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.



On Jul, 19, 2026

13 people who take Slynd and Cymbalta together, and have interactions are studied.

Slynd and Cymbalta drug interactions.

What are the common drug interactions of Slynd and Cymbalta, by gender? *:

female:

  1. Hypersensitivity
  2. Asthma exercise induced
  3. Adjustment disorder with depressed mood
  4. Blood triglycerides decreased
  5. Blood triglycerides increased
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Corneal abrasion (loss of the surface of cornea)
  8. Dehydration (dryness resulting from the removal of water)
  9. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  10. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

male:

n/a

What are the common drug interactions of Slynd and Cymbalta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)

30-39:

  1. Pain
  2. Hypersensitivity
  3. Injection site pain
  4. Insomnia (sleeplessness)
  5. Nasopharyngitis (inflammation of the nasopharynx)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 53.85%
  2. Drowsiness: 6 people, 46.15%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 46.15%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 15.38%
  5. Psoriasis (immune-mediated disease that affects the skin): 2 people, 15.38%
  6. Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 2 people, 15.38%
  7. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 15.38%
  8. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 7.69%
  9. Nasopharyngitis (inflammation of the nasopharynx): 1 person, 7.69%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Slynd and Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Slynd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Slynd and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cymbalta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on drospirenone and duloxetine hydrochloride (the active ingredients of Slynd and Cymbalta, respectively), and Slynd and Cymbalta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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