Sodium bicarbonate and Adcal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium bicarbonate (sodium bicarbonate) and Adcal (calcium carbonate). Common drug interactions include hyperglycaemia among females and subarachnoid haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium bicarbonate and Adcal. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

What is Adcal?

Adcal has active ingredients of calcium carbonate. eHealthMe is studying from 4,844 Adcal users. Check the latest studies of Adcal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

24 people who take Sodium bicarbonate and Adcal together, and have interactions are studied.

Sodium bicarbonate and Adcal drug interactions.

What are the common drug interactions of Sodium Bicarbonate and Adcal, by gender? *:

female:

Hyperglycaemia (high blood sugar)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Abortion spontaneous (naturally occurring miscarriage)
Dehydration (dryness resulting from the removal of water)
Fear of falling

male:

Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Faeces discoloured
Gait disturbance
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hydronephrosis (water inside the kidney)
Hyperkalaemia (damage to or disease of the kidney)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Lower respiratory tract infection

What are the common drug interactions of Sodium Bicarbonate and Adcal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Gait disturbance
Hyperkalaemia (damage to or disease of the kidney)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Malaise (a feeling of general discomfort or uneasiness)

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hyperglycaemia (high blood sugar)
Lower respiratory tract infection
Nausea (feeling of having an urge to vomit)
Pain
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Urinary tract infection
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Dehydration (dryness resulting from the removal of water)
Faeces discoloured

What are the existing conditions these people have? *

Ill-Defined Disorder: 7 people, 29.17%
Osteoporosis (bones weak and more likely to break): 3 people, 12.50%
Chest Pain: 3 people, 12.50%
Nausea (feeling of having an urge to vomit): 2 people, 8.33%
Itching: 2 people, 8.33%
Hypoglycemia (low blood sugar): 2 people, 8.33%
High Blood Cholesterol: 2 people, 8.33%
Dry Skin: 2 people, 8.33%
Diarrhea: 2 people, 8.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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