Sodium bicarbonate and Robinul drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium bicarbonate (sodium bicarbonate) and Robinul (glycopyrrolate). Common drug interactions include hepatic failure among females and pancreatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium bicarbonate and Robinul. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

What is Robinul?

Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.



On Jul, 18, 2026

24 people who take Sodium bicarbonate and Robinul together, and have interactions are studied.

Sodium bicarbonate and Robinul drug interactions.

What are the common drug interactions of Sodium Bicarbonate and Robinul, by gender? *:

female:

  1. Hepatic failure (liver failure)
  2. Abdominal distension
  3. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  5. Ulcer
  6. Unresponsive to stimuli
  7. Vomiting
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Depression

male:

  1. Pancreatitis (inflammation of pancreas)
  2. Acute lymphocytic leukaemia (cancer of the white blood cells)
  3. Confusional state
  4. Cough
  5. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  6. Delirium (wild excitement)
  7. Diarrhoea
  8. Dyspnoea (difficult or laboured respiration)
  9. Electrocardiogram qt prolonged
  10. Encephalopathy (functioning of the brain is affected by some agent or condition)

What are the common drug interactions of Sodium Bicarbonate and Robinul, by age (0-1 to 60+)? *:

0-1:

  1. Complex partial seizures (epileptic seizure)

2-9:

n/a

10-19:

  1. Haematocrit decreased
  2. Haemoglobin decreased
  3. Liver disorder (liver diseases)
  4. Mean cell volume decreased (less of the average red blood cell volume)
  5. Mitral valve incompetence (inefficient heart valve)
  6. Nausea (feeling of having an urge to vomit)
  7. Platelet count decreased
  8. Protein total decreased
  9. Red blood cell count decreased
  10. Respiratory failure (inadequate gas exchange by the respiratory system)

20-29:

n/a

30-39:

  1. Cardiac arrest
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  6. Anaemia (lack of blood)
  7. Pancreatitis (inflammation of pancreas)

40-49:

  1. Injury
  2. Pain
  3. Renal failure (kidney dysfunction)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Emotional disorder
  6. Emotional distress
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

  1. Hepatic failure (liver failure)

60+:

  1. Anxiety
  2. Emotional distress
  3. Nervousness
  4. Psychiatric symptom
  5. Cellulitis (infection under the skin)
  6. Fall
  7. Renal tubular necrosis (death of kidney tubules)
  8. Swelling
  9. Injury
  10. Pain

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 20.83%
  2. Premenstrual Syndrome: 4 people, 16.67%
  3. Muscle Spasms (muscle contraction): 4 people, 16.67%
  4. Hypotension (abnormally low blood pressure): 4 people, 16.67%
  5. Bradycardia (abnormally slow heart action): 4 people, 16.67%
  6. Urinary Tract Infection: 2 people, 8.33%
  7. Stress And Anxiety: 2 people, 8.33%
  8. Immunodeficiency Disorders: 2 people, 8.33%
  9. Hyperglycemia (high blood sugar): 2 people, 8.33%
  10. Essential Hypertension (primary hypertension): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sodium bicarbonate and Robinul:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sodium bicarbonate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Robinul:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sodium bicarbonate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robinul and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sodium bicarbonate and glycopyrrolate (the active ingredients of Sodium bicarbonate and Robinul, respectively), and Sodium bicarbonate and Robinul (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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