Sodium bicarbonate and Sumatriptan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium bicarbonate (sodium bicarbonate) and Sumatriptan (sumatriptan succinate). Common drug interactions include blood calcium decreased among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium bicarbonate and Sumatriptan. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

On Aug, 06, 2026

78 people who take Sodium bicarbonate and Sumatriptan together, and have interactions are studied.

Sodium bicarbonate and Sumatriptan drug interactions.

What are the common drug interactions of Sodium Bicarbonate and Sumatriptan, by gender? *:

female:

Blood calcium decreased
Blood creatinine increased
Cardiac arrest
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Drug ineffective
Maternal exposure during pregnancy (use of substance during pregnancy)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Abortion spontaneous (naturally occurring miscarriage)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

male:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Mobility decreased (ability to move is reduced)
Nephrogenic anaemia (anaemia due to kidney disease)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Quality of life decreased
Rash generalised (rash on most of body parts)
Renal impairment (severely reduced kidney function)
Renal pain (kidney pain)

What are the common drug interactions of Sodium Bicarbonate and Sumatriptan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

30-39:

Maternal exposure during pregnancy (use of substance during pregnancy)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Abortion spontaneous (naturally occurring miscarriage)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Emotional distress
Hyperhidrosis (abnormally increased sweating)
Myalgia (muscle pain)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)

40-49:

Blood calcium decreased
Dehydration (dryness resulting from the removal of water)
Haemoglobin decreased
Hypertension (high blood pressure)
Irritable bowel syndrome
Nausea (feeling of having an urge to vomit)
Obesity (having too much body fat)
Pain
Pneumonia
Vocal cord disorder

50-59:

Pain
Anaemia (lack of blood)
Cough
Hepatic failure (liver failure)
Renal failure (kidney dysfunction)
Urinary tract infection
Abdominal pain
Breast mass
Bronchial hyperreactivity
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

Anaemia (lack of blood)
Chronic kidney disease
Blood creatinine increased
Cardiac arrest
Decreased appetite
Delirium (wild excitement)
Dementia (madness)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Eye pain

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 31 people, 39.74%
Nausea And Vomiting: 27 people, 34.62%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 26 people, 33.33%
Fever: 25 people, 32.05%
Morning Sickness (sickness in morning during pregnancy): 24 people, 30.77%
Hyperemesis Gravidarum (a condition characterized by severe nausea, vomiting, weight loss, and electrolyte disturbance): 23 people, 29.49%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 22 people, 28.21%
Body Temperature Increased: 20 people, 25.64%
Immunodeficiency Common Variable: 6 people, 7.69%
High Blood Pressure: 6 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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