Sodium bicarbonate and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium bicarbonate (sodium bicarbonate) and Vimpat (lacosamide). Common drug interactions include atelectasis among females and small intestinal obstruction among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium bicarbonate and Vimpat. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,832 Vimpat users. Check the latest studies of Vimpat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

56 people who take Sodium bicarbonate and Vimpat together, and have interactions are studied.

Sodium bicarbonate and Vimpat drug interactions.

What are the common drug interactions of Sodium Bicarbonate and Vimpat, by gender? *:

female:

Atelectasis (partial or complete collapse of the lung)
Cardiotoxicity (damage to the heart muscle)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Abdominal pain upper
Anaemia (lack of blood)
Anuria (failure of the kidneys to produce urine)
Cellulitis (infection under the skin)
Cerebral toxoplasmosis (parasitic disease of brain caused by the protozoan toxoplasma gondii)
Chronic kidney disease
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)

male:

Small intestinal obstruction (blockage in small intestine)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Hypertransaminasaemia
Pyrexia (fever)
Rash
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Sodium Bicarbonate and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Agitation (state of anxiety or nervous excitement)
Anaphylactic reaction (serious allergic reaction)
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Rash
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Urticaria (rash of round, red welts on the skin that itch intensely)
Aortic dilatation
Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)

10-19:

Bradycardia (abnormally slow heart action)
Cellulitis (infection under the skin)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cytokine storm (over-protective immune response that can actually be fatal)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)
Hyperkalaemia (damage to or disease of the kidney)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)

20-29:

Drug ineffective
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Atelectasis (partial or complete collapse of the lung)
Cardiotoxicity (damage to the heart muscle)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Agitation (state of anxiety or nervous excitement)
Device failure
Insomnia (sleeplessness)
Psychomotor hyperactivity (feelings of extreme restlessness)

30-39:

Small intestinal obstruction (blockage in small intestine)
Chronic kidney disease
Emotional distress
Osteoporosis (bones weak and more likely to break)
Pain
Anuria (failure of the kidneys to produce urine)
Chest pain
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypertensive emergency

40-49:

n/a

50-59:

Anaemia (lack of blood)

60+:

Disturbance in attention
Tremor (trembling or shaking movements in one or more parts of your body)
Vertigo
Delirium (wild excitement)
General physical condition
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Somnolence (a state of near-sleep, a strong desire for sleep)
Acute psychosis (period of mentally unstable behaviour)
Cardiac failure
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 12 people, 21.43%
Sleep Disorder: 6 people, 10.71%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 10.71%
Depression: 6 people, 10.71%
Pain: 3 people, 5.36%
Nausea (feeling of having an urge to vomit): 3 people, 5.36%
Multiple Myeloma (cancer of the plasma cells): 3 people, 5.36%
Anaemia (lack of blood): 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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