Sodium chloride and Codeine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium chloride (sodium chloride) and Codeine sulfate (codeine sulfate). Common drug interactions include gastric ulcer among females and pain in extremity among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium chloride and Codeine sulfate. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium chloride?

Sodium chloride has active ingredients of sodium chloride. eHealthMe is studying from 39,559 Sodium chloride users. Check the latest studies of Sodium chloride.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

27 people who take Sodium chloride and Codeine sulfate together, and have interactions are studied.

Sodium chloride and Codeine sulfate drug interactions.

What are the common drug interactions of Sodium Chloride and Codeine Sulfate, by gender? *:

female:

Gastric ulcer (stomach ulcer)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Gastritis (inflammation of stomach)
Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haematemesis (vomiting of blood)
Haematocrit decreased
Haemoglobin decreased

male:

Pain in extremity
Arthralgia (joint pain)
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Influenza
Nausea (feeling of having an urge to vomit)
Neck pain
Nerve compression
Productive cough

What are the common drug interactions of Sodium Chloride and Codeine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal discomfort
Abdominal distension
Abdominal pain upper
Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Anxiety
Asthenia (weakness)
Blood albumin decreased
Blood calcium decreased
Blood chloride increased

30-39:

Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Hospitalisation
Infusion site swelling
Ovarian cyst (fluid filled sac of the ovary)
Fall
Infusion site extravasation (flow of (blood or lymph) from infusion site)

40-49:

Constipation
Cystic fibrosis (disease of the secretary glands)
Decreased activity
Diarrhoea
Enzyme level increased
Faeces discoloured
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hypersensitivity
Intervertebral disc protrusion (spinal disc protrusion)
Cough

50-59:

Peripheral swelling
Adrenal disorder
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dizziness
Eye infection
Fall
Fatigue (feeling of tiredness)
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Arthralgia (joint pain)
Headache (pain in head)
Influenza
Nausea (feeling of having an urge to vomit)
Neck pain
Nerve compression
Pain in extremity
Productive cough
Pyrexia (fever)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 22.22%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 5 people, 18.52%
Cystic Fibrosis (disease of the secretary glands): 4 people, 14.81%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 7.41%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 2 people, 7.41%
Galactosaemia (transformation of galactose to glucose is blocked): 2 people, 7.41%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 2 people, 7.41%
Asthma: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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