Sodium chloride and Xiidra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium chloride (sodium chloride) and Xiidra (lifitegrast). Common drug interactions include urinary retention among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium chloride and Xiidra. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium chloride?

Sodium chloride has active ingredients of sodium chloride. eHealthMe is studying from 39,559 Sodium chloride users. Check the latest studies of Sodium chloride.

What is Xiidra?

Xiidra has active ingredients of lifitegrast. eHealthMe is studying from 15,244 Xiidra users. Check the latest studies of Xiidra.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

59 people who take Sodium chloride and Xiidra together, and have interactions are studied.

Sodium chloride and Xiidra drug interactions.

What are the common drug interactions of Sodium Chloride and Xiidra, by gender? *:

female:

Urinary retention (the inability to completely or partially empty the bladder)
Urinary tract infection
Weight increased
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Alopecia (absence of hair from areas of the body)
Blood pressure increased
Compression fracture (fracture due to pressure caused by injury)
Concussion (short loss of normal brain function in response to a head injury)
Forearm fracture (fracture in between wrist to elbow)
Infusion site bruising

male:

Headache (pain in head)
Dyspnoea (difficult or laboured respiration)
Fall
Gait disturbance
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Pharyngeal mass
Renal impairment (severely reduced kidney function)
Sinus disorder (disease of sinus)
Vomiting
Back pain

What are the common drug interactions of Sodium Chloride and Xiidra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Drug hypersensitivity
Arthralgia (joint pain)
Asthma
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Device occlusion
Dizziness
Ear congestion
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)

50-59:

Arthralgia (joint pain)
Asthenia (weakness)
Back disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Dizziness
Dry eye (lack of adequate tears)
Fatigue (feeling of tiredness)
Hypersomnia (excessive daytime sleepiness (eds))
Influenza

60+:

Fall
Headache (pain in head)
Renal impairment (severely reduced kidney function)
Pain
Compression fracture (fracture due to pressure caused by injury)
Forearm fracture (fracture in between wrist to elbow)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Migraine (headache)
Rash
Seasonal allergy (allergic condition due to certain season)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 22 people, 37.29%
Immune System Disorder: 6 people, 10.17%
Hereditary Angioedema (recurrent episodes of severe swelling): 5 people, 8.47%
Pemphigoid (tense blisters on the skin): 4 people, 6.78%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 6.78%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 4 people, 6.78%
Lichen Myxoedematosus (deposition of acid mucopolysaccharides in the skin): 4 people, 6.78%
Iridocyclitis (inflammation of the iris and ciliary body of the eye): 4 people, 6.78%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 5.08%
Primary Immunodeficiency Syndrome: 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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