Soliris and Gemcitabine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Soliris (eculizumab) and Gemcitabine (gemcitabine). Common drug interactions include acute myeloid leukaemia among females and leukopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Soliris and Gemcitabine. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

What is Gemcitabine?

Gemcitabine has active ingredients of gemcitabine. eHealthMe is studying from 31,337 Gemcitabine users. Check the latest studies of Gemcitabine.

On Jul, 12, 2026

27 people who take Soliris and Gemcitabine together, and have interactions are studied.

Soliris and Gemcitabine drug interactions.

What are the common drug interactions of Soliris and Gemcitabine, by gender? *:

female:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anaemia (lack of blood)
Headache (pain in head)
Influenza
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Rhinorrhoea (watery mucus discharge from the nose)
Disease progression
Pancreatic carcinoma recurrent (pancreatic cancer - recurrent)
Rash pruritic (redness with itching)

male:

Leukopenia (less number of white blood cells in blood)
Carbohydrate antigen 19-9 increased
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Cardiac failure congestive
Haematotoxicity (toxins that destroy red blood cells)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Metastases to bone (cancer spreads to bone)
Metastases to liver (cancer spreads to liver)
Metastasis (spreadable cancer to other organ from origin)
Pancreatic carcinoma (pancreatic cancer)

What are the common drug interactions of Soliris and Gemcitabine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood lactate dehydrogenase increased
Haptoglobin decreased

50-59:

Disease progression
Carbohydrate antigen 19-9 increased
General physical health deterioration (weak health status)
Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
Hepatic failure (liver failure)
Pancreatic carcinoma recurrent (pancreatic cancer - recurrent)
Rash pruritic (redness with itching)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Haematotoxicity (toxins that destroy red blood cells)

60+:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anaemia (lack of blood)
General physical health deterioration (weak health status)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Haemolytic anaemia (anaemia due to haemolysis)
Infection
Lung cancer metastatic (lung cancer spreads to other parts)
Lymphangiosis carcinomatosa (inflammation of the lymph vessels can lead to cancer)
Renal failure (kidney dysfunction)
Respiratory distress (difficulty in breathing)

What are the existing conditions these people have? *

Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 14 people, 51.85%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 5 people, 18.52%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 5 people, 18.52%
Neoplasm Malignant (cancer tumour): 3 people, 11.11%
Breast Cancer: 3 people, 11.11%
Pancreatic Carcinoma (pancreatic cancer): 2 people, 7.41%
Non-Small Cell Lung Cancer Stage Iiib: 2 people, 7.41%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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