Soliris and Xeloda drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Soliris (eculizumab) and Xeloda (capecitabine). Common drug interactions include rhinorrhoea among females and back pain among males.
The phase IV clinical study analyzes what interactions people have when they take Soliris and Xeloda. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Soliris?
Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.
What is Xeloda?
Xeloda has active ingredients of capecitabine. It is often used in colon cancer. eHealthMe is studying from 46,649 Xeloda users. Check the latest studies of Xeloda.
13 people who take Soliris and Xeloda together, and have interactions are studied.

What are the common drug interactions of Soliris and Xeloda, by gender? *:
female:
- Rhinorrhoea (watery mucus discharge from the nose)
- Drug ineffective
- Headache (pain in head)
- Heart rate decreased
- Oropharyngeal pain
- Paralysis
- Pneumonia
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Pyrexia (fever)
- Abdominal pain
male:
- Back pain
- Dizziness
- Pneumonia
- Cancer pain
- Fall
- Hand fracture
- Hypokinesia (decreased bodily movement)
- Lung cancer metastatic (lung cancer spreads to other parts)
- Malaise (a feeling of general discomfort or uneasiness)
- Rash
What are the common drug interactions of Soliris and Xeloda, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Breast mass
- Drug ineffective
- Heart rate decreased
- Paralysis
- Pneumonia
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Pyrexia (fever)
40-49:
n/a
50-59:
- Abdominal pain
- Body temperature increased
- Death
- Influenza like illness
- Nasopharyngitis (inflammation of the nasopharynx)
- Nausea (feeling of having an urge to vomit)
- Pain
- Rhinorrhoea (watery mucus discharge from the nose)
- Toothache (tooth pain)
- Vomiting
60+:
- Back pain
- Dizziness
- Pneumonia
- Cancer pain
- Fall
- Hand fracture
- Hypokinesia (decreased bodily movement)
- Lung cancer metastatic (lung cancer spreads to other parts)
- Malaise (a feeling of general discomfort or uneasiness)
- Rash
What are the existing conditions these people have? *
- Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 6 people, 46.15%
- Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 4 people, 30.77%
- Pain: 3 people, 23.08%
- Rectal Cancer (cancer of rectum): 1 person, 7.69%
- Hepatic Neoplasm (liver tumour): 1 person, 7.69%
- Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid): 1 person, 7.69%
- Breast Cancer Metastatic: 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Soliris and Xeloda?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Soliris and Xeloda:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Soliris:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xeloda:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Soliris and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xeloda and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Pinto HP, Bhat RM, Shet D, Dandekeri S, "Compound mucocutaneous adverse effects of oral capecitabine in a patient", Indian dermatology online journal, 2014 Jan .
- Kang SM, Baek JY, Hwangbo B, Kim HY, Lee GK, Lee HS, "A case of capecitabine-induced sarcoidosis", Tuberculosis and respiratory diseases, 2012 Mar .
- Pinto HP, Bhat RM, Shet D, Dandekeri S, "Compound mucocutaneous adverse effects of oral capecitabine in a patient", Indian dermatology online journal, 2014 Jan .
- Kang SM, Baek JY, Hwangbo B, Kim HY, Lee GK, Lee HS, "A case of capecitabine-induced sarcoidosis", Tuberculosis and respiratory diseases, 2012 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on eculizumab and capecitabine (the active ingredients of Soliris and Xeloda, respectively), and Soliris and Xeloda (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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