Solu-cortef and Haldol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-cortef (hydrocortisone sodium succinate) and Haldol (haloperidol). Common drug interactions include anaemia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-cortef and Haldol. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Haldol?

Haldol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 23,102 Haldol users. Check the latest studies of Haldol.



On Jul, 19, 2026

25 people who take Solu-cortef and Haldol together, and have interactions are studied.

Solu-cortef and Haldol drug interactions.

What are the common drug interactions of Solu-Cortef and Haldol, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Sedation
  3. Haemoglobin decreased
  4. Death
  5. Electrocardiogram qt prolonged
  6. Increased appetite
  7. Respiratory depression (respiration has a rate below 12 breaths)
  8. Agitation (state of anxiety or nervous excitement)
  9. Anxiety
  10. Aspartate aminotransferase increased

male:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Pemphigoid (tense blisters on the skin)
  3. Ataxia (loss of full control of bodily movements)
  4. Blood bilirubin increased
  5. Blood lactate dehydrogenase increased
  6. Cardiac failure
  7. Coma (state of unconsciousness lasting more than six hours)
  8. Death
  9. Depressed level of consciousness
  10. Echolalia (meaningless repetition of another person's spoken words -psychiatric disorder)

What are the common drug interactions of Solu-Cortef and Haldol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Death
  2. Electrocardiogram qt prolonged
  3. Increased appetite
  4. Respiratory depression (respiration has a rate below 12 breaths)
  5. Sedation
  6. Abdominal pain
  7. Agitation (state of anxiety or nervous excitement)
  8. Amaurosis (partial or total blindness without visible change in the eye)
  9. Aphasia (damage to the parts of the brain that control language)
  10. Ataxia (loss of full control of bodily movements)

10-19:

  1. Agitation (state of anxiety or nervous excitement)
  2. Anaemia (lack of blood)
  3. Anxiety
  4. Aspartate aminotransferase increased
  5. Blood bilirubin increased
  6. Cough
  7. Decreased appetite
  8. Fatigue (feeling of tiredness)
  9. Febrile neutropenia (fever with reduced white blood cells)
  10. Haemoglobin decreased

20-29:

n/a

30-39:

  1. Pharyngitis (inflammation of the pharynx, causing a sore throat)

40-49:

  1. Anaemia (lack of blood)
  2. Hypertension (high blood pressure)
  3. Post procedural haemorrhage (post procedural bleeding)
  4. Pseudocyst (pathological collection of fluid)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Ascites (accumulation of fluid in the abdominal cavity)
  7. Hepatic failure (liver failure)
  8. Intra-abdominal haemorrhage (intra-abdominal bleeding)
  9. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  10. Pancreatitis acute (sudden inflammation of pancreas)

50-59:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Pemphigoid (tense blisters on the skin)
  3. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Haematocrit decreased
  7. Haemodynamic instability (disturbances in the blood movement in our body)
  8. Haemoglobin decreased
  9. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  10. Multi-organ failure (multisystem organ failure)

60+:

  1. Adverse drug reaction
  2. Alanine aminotransferase increased
  3. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Post procedural haemorrhage (post procedural bleeding)
  6. Respiratory distress (difficulty in breathing)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Septic shock (shock due to blood infection)
  9. White blood cell count decreased
  10. Aspartate aminotransferase increased

What are the existing conditions these people have? *

  1. Constipation: 4 people, 16.00%
  2. Nausea (feeling of having an urge to vomit): 4 people, 16.00%
  3. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 12.00%
  4. Fever: 3 people, 12.00%
  5. High Blood Cholesterol: 3 people, 12.00%
  6. Stress And Anxiety: 3 people, 12.00%
  7. Tumor: 2 people, 8.00%
  8. Hoarseness Or Changing Voice: 2 people, 8.00%
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 8.00%
  10. Back Pain: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Solu-cortef and Haldol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Haldol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Solu-cortef and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Haldol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone sodium succinate and haloperidol (the active ingredients of Solu-cortef and Haldol, respectively), and Solu-cortef and Haldol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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