Solu-cortef and Lanoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-cortef (hydrocortisone sodium succinate) and Lanoxin (digoxin). Common drug interactions include thrombocytopenia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-cortef and Lanoxin. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

On Jul, 29, 2026

21 people who take Solu-cortef and Lanoxin together, and have interactions are studied.

Solu-cortef and Lanoxin drug interactions.

What are the common drug interactions of Solu-Cortef and Lanoxin, by gender? *:

female:

Thrombocytopenia (decrease of platelets in blood)
Agitation (state of anxiety or nervous excitement)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Confusional state
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Hepatic enzyme increased
Hepatic ischaemia (liver does not get enough blood or oxygen, causing injury to liver cells)

male:

Renal failure (kidney dysfunction)
Multi-organ failure (multisystem organ failure)
Depression
Injury
Renal impairment (severely reduced kidney function)
Acidosis (build-up of carbon dioxide in the blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Fluid overload (too much fluid in the blood)
Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the common drug interactions of Solu-Cortef and Lanoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Aggression
Alanine aminotransferase increased
Arrhythmia (irregular heartbeat)
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood bilirubin increased
Bone mass decreased
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Compression fracture (fracture due to pressure caused by injury)

50-59:

n/a

60+:

Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Injury
Neutropenia (an abnormally low number of neutrophils)
Renal failure acute (rapid kidney dysfunction)
Renal impairment (severely reduced kidney function)
Respiratory disorder (respiratory disease)
Thrombocytopenia (decrease of platelets in blood)
Acidosis (build-up of carbon dioxide in the blood)
Agitation (state of anxiety or nervous excitement)

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 28.57%
Diabetes: 2 people, 9.52%
Chronic Renal Failure (kidney failure): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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