Solu-medrol and Anzemet drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Solu-medrol (methylprednisolone sodium succinate) and Anzemet (dolasetron mesylate). Common drug interactions include bone disorder among females and renal failure acute among males.
The phase IV clinical study analyzes what interactions people have when they take Solu-medrol and Anzemet. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.
What is Solu-medrol?
Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.
What is Anzemet?
Anzemet has active ingredients of dolasetron mesylate. eHealthMe is studying from 2,603 Anzemet users. Check the latest studies of Anzemet.
78 people who take Solu-medrol and Anzemet together, and have interactions are studied.

What are the common drug interactions of Solu-Medrol and Anzemet, by gender? *:
female:
- Bone disorder
- Osteonecrosis of jaw (death of bone of jaw)
- Dental caries
- Infection
- Fatigue (feeling of tiredness)
- Pleural effusion (water on the lungs)
- Vertigo
- Abdominal pain
- Pain in jaw
- Anxiety
male:
- Renal failure acute (rapid kidney dysfunction)
- Death
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Coagulopathy (blood's ability to clot is impaired)
- Fatigue (feeling of tiredness)
- Hepatic failure (liver failure)
- Hypoxia (low oxygen in tissues)
- Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
- Multi-organ failure (multisystem organ failure)
- Respiratory failure (inadequate gas exchange by the respiratory system)
What are the common drug interactions of Solu-Medrol and Anzemet, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anxiety
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Hypoaesthesia (reduced sense of touch or sensation)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Abdominal pain
- Abortion spontaneous (naturally occurring miscarriage)
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
- Acute respiratory failure
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Anaemia of chronic disease
30-39:
- Haemoglobin decreased
- Hypotension (abnormally low blood pressure)
- Abdominal pain upper
- Acidosis (build-up of carbon dioxide in the blood)
- Anoxia (low oxygen)
- Aortic valve incompetence
- Apnoea (suspension of external breathing)
- Arrhythmia (irregular heartbeat)
- Caecitis (inflammation of the cecum)
- Cardiac failure
40-49:
- Abdominal pain
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Fatigue (feeling of tiredness)
- Pain
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Sinusitis (inflammation of sinus)
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
50-59:
- Swelling
- Bone disorder
- Cough
- Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Osteonecrosis of jaw (death of bone of jaw)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Tenderness (pain or discomfort when an affected area is touched)
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Atelectasis (partial or complete collapse of the lung)
60+:
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Renal failure acute (rapid kidney dysfunction)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Hypertension (high blood pressure)
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Impaired gastric emptying
- Nausea (feeling of having an urge to vomit)
- Pleural effusion (water on the lungs)
- Weight decreased
What are the existing conditions these people have? *
- Stress And Anxiety: 16 people, 20.51%
- Breast Cancer: 14 people, 17.95%
- Anaemia (lack of blood): 13 people, 16.67%
- Multiple Myeloma (cancer of the plasma cells): 12 people, 15.38%
- Pain In Jaw: 11 people, 14.10%
- Diabetes: 9 people, 11.54%
- Joint Pain: 9 people, 11.54%
- Breast Cancer Recurrent: 9 people, 11.54%
- Sleep Disorder: 9 people, 11.54%
- Depression: 9 people, 11.54%
* Approximation only. Some reports may have incomplete information.
Do you take Solu-medrol and Anzemet?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Solu-medrol (39,410 reports)
- Anzemet (2,603 reports)
Browse all drug interactions of Solu-medrol and Anzemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Solu-medrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Anzemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Solu-medrol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Anzemet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on methylprednisolone sodium succinate and dolasetron mesylate (the active ingredients of Solu-medrol and Anzemet, respectively), and Solu-medrol and Anzemet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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