Solu-medrol and Truxima drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-medrol (methylprednisolone sodium succinate) and Truxima (rituximab-abbs). Common drug interactions include bursitis among females and urticaria among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-medrol and Truxima. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

What is Truxima?

Truxima has active ingredients of rituximab-abbs. eHealthMe is studying from 4,063 Truxima users. Check the latest studies of Truxima.



On Jul, 03, 2026

94 people who take Solu-medrol and Truxima together, and have interactions are studied.

Solu-medrol and Truxima drug interactions.

What are the common drug interactions of Solu-Medrol and Truxima, by gender? *:

female:

  1. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  2. Pyrexia (fever)
  3. Abdominal discomfort
  4. Abdominal pain
  5. Abdominal pain upper
  6. Alopecia (absence of hair from areas of the body)
  7. Anti-cyclic citrullinated peptide antibody positive
  8. Anxiety
  9. Arthralgia (joint pain)
  10. Arthropathy

male:

  1. Urticaria (rash of round, red welts on the skin that itch intensely)
  2. Laryngeal oedema (swelling of larynx)
  3. Arthralgia (joint pain)
  4. Chest discomfort
  5. Completed suicide (act of taking one's own life)
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Infusion related reaction
  8. Lip swelling
  9. Pruritus (severe itching of the skin)
  10. Pyrexia (fever)

What are the common drug interactions of Solu-Medrol and Truxima, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Electrocardiogram t wave inversion

30-39:

n/a

40-49:

  1. Urticaria (rash of round, red welts on the skin that itch intensely)
  2. Arthralgia (joint pain)
  3. Pyrexia (fever)
  4. Abdominal discomfort
  5. Abdominal pain
  6. Abdominal pain upper
  7. Alopecia (absence of hair from areas of the body)
  8. Anti-cyclic citrullinated peptide antibody positive
  9. Anxiety
  10. Arthropathy

50-59:

  1. Meningoencephalitis herpetic (inflammation of the brain and meninges by virus)

60+:

  1. Chest discomfort
  2. Chills (felling of cold)
  3. Completed suicide (act of taking one's own life)
  4. Cough
  5. Infusion related reaction
  6. Lip swelling
  7. Pruritus (severe itching of the skin)
  8. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 35 people, 37.23%
  2. Vasculitis (inflammation of a blood vessel or blood vessels): 10 people, 10.64%
  3. Burkitt's Lymphoma (cancer of the lymphatic system): 8 people, 8.51%
  4. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 6.38%
  5. Fever: 5 people, 5.32%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-medrol and Truxima?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Solu-medrol and Truxima:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Solu-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Truxima:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Solu-medrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Truxima and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone sodium succinate and rituximab-abbs (the active ingredients of Solu-medrol and Truxima, respectively), and Solu-medrol and Truxima (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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