Soma and Propulsid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Soma (carisoprodol) and Propulsid (cisapride monohydrate). Common drug interactions include cardiac failure congestive among females and oedema lower limb among males.

The phase IV clinical study analyzes what interactions people have when they take Soma and Propulsid. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Soma?

Soma has active ingredients of carisoprodol. It is often used in muscle spasms. eHealthMe is studying from 17,137 Soma users. Check the latest studies of Soma.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

On Jul, 20, 2026

51 people who take Soma and Propulsid together, and have interactions are studied.

What are the common drug interactions of Soma and Propulsid, by gender? *:

female:

Cardiac failure congestive
Chest pain
Hypertension (high blood pressure)
Weight decreased
Abdominal pain
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Hypokalaemia (low potassium)

male:

Oedema lower limb (fluid collection in tissue of lower leg)
Chest pain
Depression
Pulmonary embolism (blockage of the main artery of the lung)
Tremor (trembling or shaking movements in one or more parts of your body)
Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb)
Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
Application site reaction
Arrhythmia (irregular heartbeat)
Blood glucose fluctuation

What are the common drug interactions of Soma and Propulsid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug dependence
Abdominal pain
Aggression
Agitation (state of anxiety or nervous excitement)
Anxiety
Asthma
Depression
Dizziness
Drug abuser
Irritability

30-39:

Migraine (headache)
Abdominal pain
Alcoholism (problems with alcohol)
Cellulitis (infection under the skin)
Dependence
Diarrhoea
Difficulty in walking
Diplopia (double vision)
Drug effect decreased
Dyspnoea (difficult or laboured respiration)

40-49:

Electrocardiogram qt prolonged
Electrolyte imbalance
Dyspnoea (difficult or laboured respiration)
Oedema lower limb (fluid collection in tissue of lower leg)
Anxiety
Blood glucose fluctuation
Chest pain
Cholecystitis infective (infection of gallbladder capable to infect other organs)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Fatigue (feeling of tiredness)

50-59:

Depression
Distress
Electrocardiogram qt corrected interval prolonged
Erythema (redness of the skin)
Fall
Haematocrit decreased
Haemoglobin decreased
Heart rate increased
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hypertension (high blood pressure)

60+:

Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
Cardiac failure congestive
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary oedema (fluid accumulation in the lungs)
Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb)
Abdominal discomfort
Abdominal distension
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angiopathy (generic term for a disease of the blood vessels)
Asthenia (weakness)

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 7.84%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 7.84%
Back Pain: 4 people, 7.84%
Hypokalemia (low potassium): 3 people, 5.88%
Diabetes: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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