Sonata and Haloperidol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sonata (zaleplon) and Haloperidol (haloperidol). Common drug interactions include chest pain among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Sonata and Haloperidol. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Sonata?

Sonata has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 3,330 Sonata users. Check the latest studies of Sonata.

What is Haloperidol?

Haloperidol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 16,637 Haloperidol users. Check the latest studies of Haloperidol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

13 people who take Sonata and Haloperidol together, and have interactions are studied.

Sonata and Haloperidol drug interactions.

What are the common drug interactions of Sonata and Haloperidol, by gender? *:

female:

  1. Chest pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Decreased appetite
  5. Dizziness
  6. Fatigue (feeling of tiredness)
  7. Hypertension (high blood pressure)
  8. Memory impairment
  9. Nausea (feeling of having an urge to vomit)
  10. Pain

male:

  1. Asthenia (weakness)
  2. Diarrhoea
  3. Deafness unilateral
  4. Dizziness
  5. Eye movement disorder
  6. General physical health deterioration (weak health status)
  7. Headache (pain in head)
  8. Hemiparesis (weakness on one side of the body)
  9. Injury
  10. Loss of consciousness

What are the common drug interactions of Sonata and Haloperidol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Altered state of consciousness (altered state of mind)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Bruxism (habitual grinding of the teeth, typically during sleep)
  4. Cerebral disorder (brain disease)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Diabetes mellitus inadequate control
  7. Disturbance in attention
  8. Encephalopathy (functioning of the brain is affected by some agent or condition)
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

40-49:

  1. Cerebrovascular disorder (disease of brain)
  2. Chest pain
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  5. Fibromyalgia (a long-term condition which causes pain all over the body)
  6. Gastrointestinal pain
  7. Hypertension (high blood pressure)
  8. Non-cardiac chest pain
  9. Pancreatitis chronic (chronic inflammation of pancreas)
  10. Polyp colorectal

50-59:

n/a

60+:

  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Diarrhoea
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  6. Balance disorder
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Deafness unilateral
  9. Eye movement disorder
  10. General physical health deterioration (weak health status)

What are the existing conditions these people have? *

  1. Pain: 4 people, 30.77%
  2. Intervertebral Disc Degeneration (spinal disc degeneration): 3 people, 23.08%
  3. Stress And Anxiety: 3 people, 23.08%
  4. Nausea And Vomiting: 3 people, 23.08%
  5. Depression: 3 people, 23.08%
  6. Dissociative Disorder: 3 people, 23.08%
  7. Glossitis (infection of tongue with soreness): 3 people, 23.08%
  8. Hallucination, Auditory (perceiving sounds without auditory stimulus): 2 people, 15.38%
  9. Bipolar Disorder (mood disorder): 2 people, 15.38%
  10. Birth Control: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Sonata and Haloperidol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sonata and Haloperidol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sonata:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Haloperidol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sonata and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Haloperidol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on zaleplon and haloperidol (the active ingredients of Sonata and Haloperidol, respectively), and Sonata and Haloperidol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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