Soolantra and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Soolantra (ivermectin) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include headache among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Soolantra and Hydroxyzine. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Soolantra?

Soolantra has active ingredients of ivermectin. eHealthMe is studying from 1,068 Soolantra users. Check the latest studies of Soolantra.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

On Jul, 17, 2026

31 people who take Soolantra and Hydroxyzine together, and have interactions are studied.

Soolantra and Hydroxyzine drug interactions.

What are the common drug interactions of Soolantra and Hydroxyzine, by gender? *:

female:

Headache (pain in head)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)
Sinusitis (inflammation of sinus)
Upper respiratory tract infection
Influenza
Fatigue (feeling of tiredness)
Gastrointestinal viral infection (virus infection of gastrointestinal tract)
Abnormal dreams

male:

Chronic kidney disease
Osteonecrosis (death of bone)
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Dry eye (lack of adequate tears)
Dry skin
Hand fracture
Injection site pruritus (severe itching at injection site)
Injection site swelling
Rosacea (a skin condition that causes facial redness)
Sinusitis (inflammation of sinus)

What are the common drug interactions of Soolantra and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Headache (pain in head)
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
Sinusitis (inflammation of sinus)
Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)
Upper respiratory tract infection
Gastrointestinal viral infection (virus infection of gastrointestinal tract)
Influenza
Staphylococcal infection (an infection with staphylococcus bacteria)
Urinary tract infection

40-49:

Chronic kidney disease
Osteonecrosis (death of bone)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Blood creatinine increased
Bone density decreased
Emotional distress
Erythema (redness of the skin)
Hip arthroplasty
Pain
Renal impairment (severely reduced kidney function)

50-59:

Abnormal dreams
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Dizziness
Dry eye (lack of adequate tears)
Dry mouth
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypersomnia (excessive daytime sleepiness (eds))
Influenza

60+:

Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 8 people, 25.81%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 19.35%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 6 people, 19.35%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 12.90%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 9.68%
Lichen Myxoedematosus (deposition of acid mucopolysaccharides in the skin): 3 people, 9.68%
Irritable Bowel Syndrome: 2 people, 6.45%
Hiv Infection: 2 people, 6.45%
Drowsiness: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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