Sotret and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sotret (isotretinoin) and Prilosec (omeprazole). Common drug interactions include chronic kidney disease among females and normal newborn among males.

The phase IV clinical study analyzes what interactions people have when they take Sotret and Prilosec. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Sotret?

Sotret has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 9,023 Sotret users. Check the latest studies of Sotret.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.



On Jul, 21, 2026

11 people who take Sotret and Prilosec together, and have interactions are studied.

Sotret and Prilosec drug interactions.

What are the common drug interactions of Sotret and Prilosec, by gender? *:

female:

  1. Chronic kidney disease
  2. Alopecia (absence of hair from areas of the body)
  3. Anaemia (lack of blood)
  4. Blood sodium decreased
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  6. Colitis (inflammation of colon)
  7. Colitis ulcerative (inflammation of colon with ulcer)
  8. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  9. Cough
  10. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

male:

  1. Normal newborn

What are the common drug interactions of Sotret and Prilosec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Anxiety
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Cough
  4. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  5. Depression
  6. Emotional distress
  7. Inflammatory bowel disease
  8. Oropharyngeal pain
  9. Pharyngeal erythema (pharyngeal redness)

10-19:

n/a

20-29:

  1. Normal newborn
  2. Abdominal discomfort
  3. Abdominal pain upper
  4. Alopecia (absence of hair from areas of the body)
  5. Dyspepsia (indigestion)
  6. Hair colour changes
  7. Hallucination, auditory (perceiving sounds without auditory stimulus)
  8. Headache (pain in head)
  9. Infection parasitic
  10. Memory impairment

30-39:

n/a

40-49:

  1. Anaemia (lack of blood)
  2. Colitis (inflammation of colon)
  3. Colitis ulcerative (inflammation of colon with ulcer)
  4. Diarrhoea
  5. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  6. Gastrointestinal oedema (excessive build-up of fluid in the gastrointestinal tract tissues)
  7. Inflammatory bowel disease
  8. Irritable bowel syndrome
  9. Lipase increased
  10. Pancreatitis (inflammation of pancreas)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

60+:

  1. Abdominal discomfort
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  3. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  4. Dizziness
  5. Insomnia (sleeplessness)
  6. Loss of consciousness
  7. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 18.18%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 18.18%
  3. Stress And Anxiety: 1 person, 9.09%
  4. Sleep Disorder: 1 person, 9.09%
  5. Petit Mal Epilepsy (absence seizure): 1 person, 9.09%
  6. Pain: 1 person, 9.09%
  7. Muscle Aches (muscle pain): 1 person, 9.09%
  8. Menopause (end of monthly cycles in women): 1 person, 9.09%
  9. Irritable Bowel Syndrome: 1 person, 9.09%
  10. Inflammation: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sotret and Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sotret:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sotret and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prilosec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on isotretinoin and omeprazole (the active ingredients of Sotret and Prilosec, respectively), and Sotret and Prilosec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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