Sovaldi and Clexane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sovaldi (sofosbuvir) and Clexane (enoxaparin sodium). Common drug interactions include balance disorder among females and hepatic neoplasm among males.

The phase IV clinical study analyzes what interactions people have when they take Sovaldi and Clexane. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Sovaldi?

Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.

On Jul, 12, 2026

19 people who take Sovaldi and Clexane together, and have interactions are studied.

What are the common drug interactions of Sovaldi and Clexane, by gender? *:

female:

Balance disorder
Head injury
Aortic valve stenosis (narrowing of the aortic valve)
Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
Infection
Pleural effusion (water on the lungs)
Pneumonia
Renal impairment (severely reduced kidney function)
Sepsis (a severe blood infection that can lead to organ failure and death)

male:

Hepatic neoplasm (liver tumour)
Thrombosis (formation of a blood clot inside a blood vessel)
Hyperkalaemia (damage to or disease of the kidney)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Oedema peripheral (superficial swelling)
Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
Renal failure (kidney dysfunction)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Haemorrhage (bleeding)
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)

What are the common drug interactions of Sovaldi and Clexane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hepatic vein thrombosis (obstruction in the veins of the liver caused by a blood clot)
Hepatocellular carcinoma (liver cancer)
Hepatic neoplasm (liver tumour)

40-49:

Hepatic neoplasm (liver tumour)

50-59:

Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
Hyperkalaemia (damage to or disease of the kidney)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Oedema peripheral (superficial swelling)
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Balance disorder
Head injury
Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
Infection
Internal fixation of fracture
Joint swelling
Muscle swelling
Myalgia (muscle pain)
Osteoporosis (bones weak and more likely to break)
Pain

What are the existing conditions these people have? *

Hepatitis C: 9 people, 47.37%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 6 people, 31.58%
Stress And Anxiety: 3 people, 15.79%
Hiv Infection: 3 people, 15.79%
Hepatitis C Antibody Positive: 3 people, 15.79%
Insomnia (sleeplessness): 2 people, 10.53%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.26%
Drug Dependence: 1 person, 5.26%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.26%
Anaemia (lack of blood): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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