Sovaldi and Effexor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sovaldi (sofosbuvir) and Effexor (venlafaxine hydrochloride). Common drug interactions include dizziness among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Sovaldi and Effexor. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Sovaldi?

Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

On Jul, 17, 2026

27 people who take Sovaldi and Effexor together, and have interactions are studied.

What are the common drug interactions of Sovaldi and Effexor, by gender? *:

female:

Dizziness
Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Hepatic failure (liver failure)
Muscular weakness (muscle weakness)
Renal failure (kidney dysfunction)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Blood bilirubin increased
Chills (felling of cold)

male:

Headache (pain in head)
Blood creatine phosphokinase increased
Dizziness
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Mood altered (changes in mood)
Pain
Rash
Violence-related symptom
Migraine (headache)

What are the common drug interactions of Sovaldi and Effexor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dizziness
Epistaxis (bleed from the nose)
Fatigue (feeling of tiredness)
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Pain
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

30-39:

Blood creatine phosphokinase increased
Myalgia (muscle pain)
Arthralgia (joint pain)
Hypoaesthesia (reduced sense of touch or sensation)
Neutrophilia

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Clumsiness (a lack of coordination or elegance)
Hyperbilirubinaemia (excess of bilirubin in the blood)

50-59:

Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Dizziness
Haemoglobin decreased
Insomnia (sleeplessness)
Muscular weakness (muscle weakness)
Pruritus (severe itching of the skin)
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Hepatic failure (liver failure)
Renal failure (kidney dysfunction)
Muscular weakness (muscle weakness)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Abnormal behaviour
Anger
Death
Dyspnoea exertional (breathlessness or shortness of breath)
Headache (pain in head)
Hordeolum (small collection of pus (abscess) on the eyelid)

What are the existing conditions these people have? *

Hepatitis C: 15 people, 55.56%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 11.11%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 11.11%
Oedema (fluid collection in tissue): 2 people, 7.41%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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