Spiriva respimat and Nitrostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spiriva respimat (tiotropium bromide) and Nitrostat (nitroglycerin). Common drug interactions include nuclear magnetic resonance imaging brain among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Spiriva respimat and Nitrostat. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Spiriva respimat?

Spiriva respimat has active ingredients of tiotropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 9,788 Spiriva respimat users. Check the latest studies of Spiriva respimat.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.



On Jul, 19, 2026

44 people who take Spiriva respimat and Nitrostat together, and have interactions are studied.

Spiriva respimat and Nitrostat drug interactions.

What are the common drug interactions of Spiriva Respimat and Nitrostat, by gender? *:

female:

  1. Nuclear magnetic resonance imaging brain
  2. Pain in extremity
  3. Parkinson's disease
  4. Pericardial effusion (fluid around the heart)
  5. Pleural effusion (water on the lungs)
  6. Pulmonary sepsis (pus in lungs)
  7. Rash
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Skin disorder (skin disease)
  10. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

male:

  1. Blood glucose increased
  2. Dyspnoea (difficult or laboured respiration)
  3. Productive cough
  4. Rectal fissure (painful condition in which a cut or tear occurs in the anus)
  5. Renal cyst (kidney cyst)
  6. Blood pressure increased
  7. Dyspnoea exertional (breathlessness or shortness of breath)
  8. Epistaxis (bleed from the nose)
  9. Oxygen saturation decreased
  10. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the common drug interactions of Spiriva Respimat and Nitrostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

50-59:

  1. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  2. Viral infection
  3. General symptom
  4. Pneumonia
  5. Cardiac disorder
  6. Coronary arterial stent insertion
  7. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  8. Loss of consciousness
  9. Pleural effusion (water on the lungs)
  10. Abscess limb (limb infection)

60+:

  1. Gait disturbance
  2. Productive cough
  3. Respiratory tract infection
  4. Upper limb fracture
  5. Upper respiratory tract infection
  6. Weight decreased
  7. Dyspnoea at rest (difficult or laboured breathing during rest)
  8. Dysuria (painful or difficult urination)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

What are the existing conditions these people have? *

  1. Wheezing (a high-pitched whistling sound made while you breath): 6 people, 13.64%
  2. High Blood Pressure: 4 people, 9.09%
  3. Constipation: 4 people, 9.09%
  4. Pain: 3 people, 6.82%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.82%
  6. Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 6.82%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva respimat and Nitrostat?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Spiriva respimat and Nitrostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spiriva respimat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nitrostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Spiriva respimat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrostat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tiotropium bromide and nitroglycerin (the active ingredients of Spiriva respimat and Nitrostat, respectively), and Spiriva respimat and Nitrostat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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