Spiriva respimat and Olopatadine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spiriva respimat (tiotropium bromide) and Olopatadine hydrochloride (olopatadine hydrochloride). Common drug interactions include infusion related reaction among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Spiriva respimat and Olopatadine hydrochloride. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Spiriva respimat?

Spiriva respimat has active ingredients of tiotropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 9,788 Spiriva respimat users. Check the latest studies of Spiriva respimat.

What is Olopatadine hydrochloride?

Olopatadine hydrochloride has active ingredients of olopatadine hydrochloride. eHealthMe is studying from 4,420 Olopatadine hydrochloride users. Check the latest studies of Olopatadine hydrochloride.

On Jul, 10, 2026

31 people who take Spiriva respimat and Olopatadine hydrochloride together, and have interactions are studied.

Spiriva respimat and Olopatadine hydrochloride drug interactions.

What are the common drug interactions of Spiriva Respimat and Olopatadine Hydrochloride, by gender? *:

female:

Infusion related reaction
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Oropharyngeal pain
Productive cough
Renal failure (kidney dysfunction)
Respiratory tract congestion (blockage on respiratory system)
Weight increased
Agitation (state of anxiety or nervous excitement)
Alopecia (absence of hair from areas of the body)

male:

Cellulitis (infection under the skin)
Drug ineffective
Stomatitis (inflammation of mucous membrane of mouth)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Epistaxis (bleed from the nose)
Eye irritation
Eye oedema (swelling or thickening of the macula, the area of the retina responsible for central vision)
Eye pruritus (eye itching)
Gastric ulcer (stomach ulcer)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Spiriva Respimat and Olopatadine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Epistaxis (bleed from the nose)
Eye irritation
Eye oedema (swelling or thickening of the macula, the area of the retina responsible for central vision)
Eye pruritus (eye itching)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypersensitivity
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Oropharyngeal pain

20-29:

n/a

30-39:

n/a

40-49:

Ear infection
Erythema (redness of the skin)
Eye disorder
Fall
Fluid retention (an abnormal accumulation of fluid in the blood)
Flushing (the warm, red condition of human skin)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Head injury
Headache (pain in head)

50-59:

Multiple allergies (allergy to multiple agents)
Sinusitis (inflammation of sinus)
Abdominal discomfort
Abdominal pain upper
Abdominal tenderness
Fatigue (feeling of tiredness)
Headache (pain in head)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Infusion site bruising
Infusion site erythema (reddening of the skin at infusion site)

60+:

Cellulitis (infection under the skin)
Drug ineffective
Oesophageal candidiasis (fungal infection of oesophagus)
Renal failure (kidney dysfunction)
Skin erosion (a discontinuity of the skin)
Stomatitis (inflammation of mucous membrane of mouth)
Weight increased
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Arthropod sting (arthropod bite)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 16 people, 51.61%
Asthma: 8 people, 25.81%
Primary Immunodeficiency Syndrome: 5 people, 16.13%
Insomnia (sleeplessness): 3 people, 9.68%
Urticaria Chronic (long lasting rash of round, red welts on the skin that itch intensely): 2 people, 6.45%
Productive Cough: 2 people, 6.45%
Hereditary Angioedema (recurrent episodes of severe swelling): 2 people, 6.45%
Headache (pain in head): 2 people, 6.45%
Allergic Rhinitis: 2 people, 6.45%
Acne (skin problems that cause pimples): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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