Spiriva respimat and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spiriva respimat (tiotropium bromide) and Prograf (tacrolimus). Common drug interactions include immunosuppression among females and hyponatraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Spiriva respimat and Prograf. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Spiriva respimat?

Spiriva respimat has active ingredients of tiotropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 9,788 Spiriva respimat users. Check the latest studies of Spiriva respimat.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

On Jul, 10, 2026

24 people who take Spiriva respimat and Prograf together, and have interactions are studied.

Spiriva respimat and Prograf drug interactions.

What are the common drug interactions of Spiriva Respimat and Prograf, by gender? *:

female:

Immunosuppression
Infection susceptibility increased
Intra-abdominal haematoma (intra-abdominal localized swelling filled with blood)
Marrow hyperplasia (increased bone marrow)
Pulmonary mass
Skin hypopigmentation (loss of skin colour)
Thrombocytopenia (decrease of platelets in blood)
Upper limb fracture
Infusion site bruising
Lung transplant rejection (failure of lung transplant)

male:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Pulmonary embolism (blockage of the main artery of the lung)
Oedema peripheral (superficial swelling)

What are the common drug interactions of Spiriva Respimat and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Immunosuppression
Infection susceptibility increased
Intra-abdominal haematoma (intra-abdominal localized swelling filled with blood)
Marrow hyperplasia (increased bone marrow)
Pulmonary mass
Skin hypopigmentation (loss of skin colour)
Thrombocytopenia (decrease of platelets in blood)
Upper limb fracture
Rales (an abnormal respiratory sound characterized by fine crackles)
Wheezing (a high-pitched whistling sound made while you breath)

60+:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Pulmonary embolism (blockage of the main artery of the lung)
Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

High Blood Pressure: 16 people, 66.67%
Type 2 Diabetes: 2 people, 8.33%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 8.33%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva respimat and Prograf?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously