Spiriva respimat and Ranexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spiriva respimat (tiotropium bromide) and Ranexa (ranolazine). Common drug interactions include nausea among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Spiriva respimat and Ranexa. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Spiriva respimat?

Spiriva respimat has active ingredients of tiotropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 9,788 Spiriva respimat users. Check the latest studies of Spiriva respimat.

What is Ranexa?

Ranexa has active ingredients of ranolazine. It is often used in angina. eHealthMe is studying from 11,758 Ranexa users. Check the latest studies of Ranexa.

On Aug, 02, 2026

17 people who take Spiriva respimat and Ranexa together, and have interactions are studied.

Spiriva respimat and Ranexa drug interactions.

What are the common drug interactions of Spiriva Respimat and Ranexa, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Death
Intervertebral disc degeneration (spinal disc degeneration)
Syncope (loss of consciousness with an inability to maintain postural tone)
Blood pressure increased
Headache (pain in head)
Dizziness
Anxiety
Colitis ulcerative (inflammation of colon with ulcer)
Constipation

male:

Death
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hospitalisation
Joint injury
Rectal haemorrhage (bleeding from anus)
Abdominal pain upper
Back injury
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Eye irritation

What are the common drug interactions of Spiriva Respimat and Ranexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Blood pressure increased
Colitis ulcerative (inflammation of colon with ulcer)
Constipation
Headache (pain in head)
Heart rate decreased
Heart rate increased
Influenza like illness
Kidney infection
Lethargy (tiredness)

50-59:

n/a

60+:

Death
Intervertebral disc degeneration (spinal disc degeneration)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back injury
Balance disorder
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Diarrhoea
Disease progression

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 23.53%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 17.65%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 17.65%
Pain: 2 people, 11.76%
Heart Disease: 2 people, 11.76%
High Blood Cholesterol: 2 people, 11.76%
Enlarged Prostate: 2 people, 11.76%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 11.76%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 2 people, 11.76%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva respimat and Ranexa?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously