Spiriva respimat and Tyvaso dpi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spiriva respimat (tiotropium bromide) and Tyvaso dpi (treprostinil). Common drug interactions include conjunctival haemorrhage among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Spiriva respimat and Tyvaso dpi. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Spiriva respimat?

Spiriva respimat has active ingredients of tiotropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 9,788 Spiriva respimat users. Check the latest studies of Spiriva respimat.

What is Tyvaso dpi?

Tyvaso dpi has active ingredients of treprostinil. eHealthMe is studying from 3,551 Tyvaso dpi users. Check the latest studies of Tyvaso dpi.

On Jul, 07, 2026

50 people who take Spiriva respimat and Tyvaso dpi together, and have interactions are studied.

Spiriva respimat and Tyvaso dpi drug interactions.

What are the common drug interactions of Spiriva Respimat and Tyvaso Dpi, by gender? *:

female:

Conjunctival haemorrhage (bleeding underneath the conjunctiva)
Constipation
Death
Disease progression
Dyspepsia (indigestion)
Eye pain
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastric disorder (disease of stomach)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypoacusis (loss of hearing)

male:

Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased
Epistaxis (bleed from the nose)
Lower respiratory tract infection
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Respiratory failure (inadequate gas exchange by the respiratory system)
Tinea pedis (a contagious skin infection caused by the ringworm fungus)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Drug tolerance decreased
Oropharyngeal pain

What are the common drug interactions of Spiriva Respimat and Tyvaso Dpi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Dyspnoea exertional (breathlessness or shortness of breath)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased
Pneumonia
Asthenia (weakness)
Dry mouth
Pneumonia legionella (pneumonia caused by the bacteria legionella)

60+:

Cough
Dyspnoea (difficult or laboured respiration)
Oropharyngeal pain
Paranasal sinus discomfort
Superficial vein prominence
Acidosis (build-up of carbon dioxide in the blood)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Heart rate increased
Pulmonary hypertension (increase in blood pressure in the lung artery)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 49 people, 98.00%

* Approximation only. Some reports may have incomplete information.

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