Sporanox and Colace drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sporanox (itraconazole) and Colace (docusate ). Common drug interactions include platelet count decreased among females and atelectasis among males.
The phase IV clinical study analyzes what interactions people have when they take Sporanox and Colace. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.
What is Sporanox?
Sporanox has active ingredients of itraconazole. It is often used in fungal infection. eHealthMe is studying from 6,137 Sporanox users. Check the latest studies of Sporanox.
What is Colace?
Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.
30 people who take Sporanox and Colace together, and have interactions are studied.

What are the common drug interactions of Sporanox and Colace, by gender? *:
female:
- Platelet count decreased
- Renal failure (kidney dysfunction)
- White blood cell count decreased
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Anaemia (lack of blood)
- Anxiety
- Cardiac failure congestive
- Clostridium difficile sepsis (infection(pus formation) of colon by clostridium difficile bacteria)
- Drug effect decreased
- Escherichia infection (bacterial infection by escherichia coli)
male:
- Atelectasis (partial or complete collapse of the lung)
- Fatigue (feeling of tiredness)
- Haematemesis (vomiting of blood)
- Herpes dermatitis (skin inflammation caused by a herpes simplex virus (hsv))
- Hypotension (abnormally low blood pressure)
- Keratitis herpetic (inflammation of the cornea due to infection of a present or previous herpes simplex virus)
- Leukopenia (less number of white blood cells in blood)
- Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
- Muscular weakness (muscle weakness)
- Peripheral sensorimotor neuropathy (damage to one or more of your peripheral nerves)
What are the common drug interactions of Sporanox and Colace, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Acute respiratory failure
- Anxiety
- Blood creatinine increased
- Candidiasis (candidiasis or thrush is a fungal infection)
- Cardiac failure congestive
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Hypertension (high blood pressure)
- Leukopenia (less number of white blood cells in blood)
40-49:
- Appetite disorder (abnormal eating habits)
- Asthenia (weakness)
- Atrioventricular block second degree (heart block second degree)
- Bradycardia (abnormally slow heart action)
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Sleep disorder
50-59:
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
- Nausea (feeling of having an urge to vomit)
- Oedema (fluid collection in tissue)
- Oedema peripheral (superficial swelling)
- Oxygen saturation decreased
- Pain
- Pain in extremity
- Pulmonary mass
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Urine output decreased
60+:
- Fatigue (feeling of tiredness)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Cough
- Pleural effusion (water on the lungs)
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
- Diarrhoea
- Haematocrit decreased
- Haematoma (collection of blood outside the blood vessels)
- Platelet count decreased
- Pulmonary oedema (fluid accumulation in the lungs)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 8 people, 26.67%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 20.00%
- Immunodeficiency Common Variable: 3 people, 10.00%
- Pain: 2 people, 6.67%
- Nausea (feeling of having an urge to vomit): 2 people, 6.67%
- Insomnia (sleeplessness): 2 people, 6.67%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 6.67%
- Cytomegalovirus Infection: 2 people, 6.67%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Sporanox and Colace?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Sporanox and Colace:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sporanox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Colace:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sporanox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Colace and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on itraconazole and docusate (the active ingredients of Sporanox and Colace, respectively), and Sporanox and Colace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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