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Sporanox and Hydroxyurea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sporanox (itraconazole) and Hydroxyurea (hydroxyurea). Common drug interactions include road traffic accident among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Sporanox and Hydroxyurea. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Sporanox?

Sporanox has active ingredients of itraconazole. It is often used in fungal infection. eHealthMe is studying from 6,137 Sporanox users. Check the latest studies of Sporanox.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

On Jul, 30, 2026

16 people who take Sporanox and Hydroxyurea together, and have interactions are studied.

Sporanox and Hydroxyurea drug interactions.

What are the common drug interactions of Sporanox and Hydroxyurea, by gender? *:

female:

  1. Road traffic accident
  2. Asthenia (weakness)
  3. Gastroenteritis (inflammation of stomach and intestine)
  4. Mitral valve stenosis (narrowing of mitral valve)
  5. Ataxia (loss of full control of bodily movements)
  6. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  7. Hypoglycaemia (deficiency of glucose in the bloodstream)
  8. Injury
  9. Multiple injuries
  10. Pulmonary valve incompetence

male:

  1. Blood creatinine increased
  2. Calculus urinary (stone in urinary system)
  3. Groin pain
  4. Loin pain (pain originates from kidney)

What are the common drug interactions of Sporanox and Hydroxyurea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood creatinine increased
  2. Calculus urinary (stone in urinary system)

50-59:

n/a

60+:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Hypertension (high blood pressure)
  3. Ataxia (loss of full control of bodily movements)
  4. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  5. Hypoglycaemia (deficiency of glucose in the bloodstream)
  6. Injury
  7. Multiple injuries
  8. Pulmonary valve incompetence
  9. Confusional state
  10. Fluid overload (too much fluid in the blood)

What are the existing conditions these people have? *

  1. Essential Thrombocythaemia (chronic blood cancer): 6 people, 37.50%
  2. Hidradenitis (chronic disease of a type of sweat gland): 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sporanox and Hydroxyurea?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sporanox and Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sporanox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sporanox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyurea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on itraconazole and hydroxyurea (the active ingredients of Sporanox and Hydroxyurea, respectively), and Sporanox and Hydroxyurea (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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