Sprintec and Klonopin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sprintec (ethinyl estradiol; norgestimate) and Klonopin (clonazepam). Common drug interactions include nasal congestion among females and aortic valve incompetence among males.

The phase IV clinical study analyzes what interactions people have when they take Sprintec and Klonopin. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Sprintec?

Sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 4,397 Sprintec users. Check the latest studies of Sprintec.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

On Jul, 15, 2026

58 people who take Sprintec and Klonopin together, and have interactions are studied.

Sprintec and Klonopin drug interactions.

What are the common drug interactions of Sprintec and Klonopin, by gender? *:

female:

Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)
Ovarian cyst (fluid filled sac of the ovary)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sinusitis (inflammation of sinus)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Oropharyngeal pain
Dizziness

male:

Aortic valve incompetence
Atrioventricular block first degree (heart block first degree)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Tricuspid valve incompetence (inefficient heart valve)
Upper respiratory tract infection
Cardiac arrest
Drug abuse
Poisoning
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Dilatation ventricular

What are the common drug interactions of Sprintec and Klonopin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain lower
Vomiting

20-29:

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Tonsillitis (inflammation of tonsil)
Dizziness
Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating)
Fatigue (feeling of tiredness)
Hunger
Libido increased (increased sexual urge to have sex)
Malaise (a feeling of general discomfort or uneasiness)
Migraine with aura (headache with vision weakness)
Oropharyngeal pain

30-39:

Sinusitis (inflammation of sinus)
Influenza
Aortic valve incompetence
Atrioventricular block first degree (heart block first degree)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Dilatation ventricular
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Headache (pain in head)
Infusion site bruising

40-49:

Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea exertional (breathlessness or shortness of breath)
Epicondylitis (tennis elbow)
Hepatic enzyme increased
Hyperlipidaemia (presence of excess lipids in the blood)
Hypersomnia (excessive daytime sleepiness (eds))
Hypertension (high blood pressure)
Iron deficiency

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 26 people, 44.83%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 17 people, 29.31%
Sleep Disorder: 8 people, 13.79%
Migraine (headache): 5 people, 8.62%
Immunodeficiency Common Variable: 5 people, 8.62%
Acne (skin problems that cause pimples): 4 people, 6.90%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 5.17%
Hypersensitivity: 3 people, 5.17%
Drowsiness: 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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