Sprintec and Xopenex hfa drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sprintec (ethinyl estradiol; norgestimate) and Xopenex hfa (levalbuterol tartrate). Common drug interactions include ankylosing spondylitis among females.
The phase IV clinical study analyzes what interactions people have when they take Sprintec and Xopenex hfa. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Sprintec?
Sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 4,397 Sprintec users. Check the latest studies of Sprintec.
What is Xopenex hfa?
Xopenex hfa has active ingredients of levalbuterol tartrate. It is often used in asthma. eHealthMe is studying from 2,529 Xopenex hfa users. Check the latest studies of Xopenex hfa.
22 people who take Sprintec and Xopenex hfa together, and have interactions are studied.

What are the common drug interactions of Sprintec and Xopenex Hfa, by gender? *:
female:
- Ankylosing spondylitis (type of arthritis affecting the spine)
- Nausea (feeling of having an urge to vomit)
- Intervertebral disc protrusion (spinal disc protrusion)
- Nerve injury
- Peroneal nerve palsy
- Pyrexia (fever)
- Rash
- Renal injury (kidney injury)
- Renal tubular necrosis (death of kidney tubules)
- Sinusitis (inflammation of sinus)
male:
n/a
What are the common drug interactions of Sprintec and Xopenex Hfa, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Ankylosing spondylitis (type of arthritis affecting the spine)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Osteomalacia (softening of the bones due to a lack of vitamin d)
- Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
- Intervertebral disc protrusion (spinal disc protrusion)
- Nausea (feeling of having an urge to vomit)
- Nerve injury
- Peroneal nerve palsy
- Vitamin d deficiency
- Back pain
30-39:
- Pyrexia (fever)
- Rash
- Vomiting
- Arthralgia (joint pain)
- Decreased appetite
- Fatigue (feeling of tiredness)
- Insomnia (sleeplessness)
- Procedural pain
- Nausea (feeling of having an urge to vomit)
- Abdominal pain
40-49:
- Chronic kidney disease
- Renal injury (kidney injury)
- Renal tubular necrosis (death of kidney tubules)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Accident
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 54.55%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 40.91%
- Sleep Disorder: 5 people, 22.73%
- Drowsiness: 4 people, 18.18%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sprintec (4,397 reports)
- Xopenex hfa (2,529 reports)
Browse all drug interactions of Sprintec and Xopenex hfa:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sprintec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xopenex hfa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sprintec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xopenex hfa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate and levalbuterol tartrate (the active ingredients of Sprintec and Xopenex hfa, respectively), and Sprintec and Xopenex hfa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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