Sprycel and Pradaxa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sprycel (dasatinib) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include haemorrhage among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Sprycel and Pradaxa. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Sprycel?

Sprycel has active ingredients of dasatinib. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 29,788 Sprycel users. Check the latest studies of Sprycel.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

19 people who take Sprycel and Pradaxa together, and have interactions are studied.

What are the common drug interactions of Sprycel and Pradaxa, by gender? *:

female:

Haemorrhage (bleeding)
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
Metastases to meninges (cancer spreads to meninges)
Dehydration (dryness resulting from the removal of water)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure (kidney dysfunction)
Diarrhoea
Agitation (state of anxiety or nervous excitement)

male:

Dyspnoea (difficult or laboured respiration)
Haematochezia (passage of stools containing blood)
Drug ineffective
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Fall
Haematoma (collection of blood outside the blood vessels)
Muscle spasms (muscle contraction)
Oedema mouth (swelling of mouth)
Oedema peripheral (superficial swelling)
Periorbital oedema (swelling around the eyes)

What are the common drug interactions of Sprycel and Pradaxa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Haemorrhage (bleeding)

60+:

Haematochezia (passage of stools containing blood)
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Essential hypertension (primary hypertension)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure (kidney dysfunction)
Agitation (state of anxiety or nervous excitement)
Angioedema (rapid swelling of the dermis)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 14 people, 73.68%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 15.79%
Traumatic Injury Of The Bladder And Urethra: 1 person, 5.26%
Radicular Pain (pain ""radiated"" along the dermatome (sensory distribution) of a nerve due to inflammation): 1 person, 5.26%
Pain: 1 person, 5.26%
Hypersensitivity: 1 person, 5.26%
High Blood Pressure: 1 person, 5.26%
Fracture Pain: 1 person, 5.26%
Diabetes: 1 person, 5.26%
Chronic Myeloid Leukaemia (In Remission): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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