Stadol and Lomotil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Stadol (butorphanol tartrate) and Lomotil (atropine sulfate; diphenoxylate hydrochloride). Common drug interactions include cellulitis among females and accident among males.

The phase IV clinical study analyzes what interactions people have when they take Stadol and Lomotil. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Stadol?

Stadol has active ingredients of butorphanol tartrate. It is often used in migraine. eHealthMe is studying from 5,546 Stadol users. Check the latest studies of Stadol.

What is Lomotil?

Lomotil has active ingredients of atropine sulfate; diphenoxylate hydrochloride. It is often used in diarrhea. eHealthMe is studying from 19,184 Lomotil users. Check the latest studies of Lomotil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

11 people who take Stadol and Lomotil together, and have interactions are studied.

Stadol and Lomotil drug interactions.

What are the common drug interactions of Stadol and Lomotil, by gender? *:

female:

  1. Cellulitis (infection under the skin)
  2. Chronic kidney disease
  3. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  4. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  5. Depression
  6. Drug dependence
  7. Drug hypersensitivity
  8. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  9. Dysgeusia (disorder of the sense of taste)
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Accident
  2. Drug dependence

What are the common drug interactions of Stadol and Lomotil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Accident

30-39:

  1. Drug addiction
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Dysgeusia (disorder of the sense of taste)
  4. Irritability
  5. Road traffic accident
  6. Vomiting

40-49:

  1. Apnoea (suspension of external breathing)
  2. Chronic kidney disease
  3. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

50-59:

  1. Abscess limb (limb infection)
  2. Anal abscess
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Genital abscess (build up of pus in genital)
  5. Herpes zoster
  6. Influenza like illness
  7. Infusion related reaction
  8. Insomnia (sleeplessness)
  9. Intervertebral disc protrusion (spinal disc protrusion)
  10. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

60+:

n/a

What are the existing conditions these people have? *

  1. Weight Decreased: 1 person, 9.09%
  2. Type 2 Diabetes: 1 person, 9.09%
  3. Pain: 1 person, 9.09%
  4. Joint Pain: 1 person, 9.09%
  5. Hypotension (abnormally low blood pressure): 1 person, 9.09%
  6. Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 9.09%
  7. Discomfort: 1 person, 9.09%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%
  9. Colon Spastic (stiffness of colon): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Stadol and Lomotil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Stadol and Lomotil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Stadol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lomotil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Stadol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lomotil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on butorphanol tartrate and atropine sulfate; diphenoxylate hydrochloride (the active ingredients of Stadol and Lomotil, respectively), and Stadol and Lomotil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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