Starlix and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Starlix (nateglinide) and Reglan (metoclopramide hydrochloride). Common drug interactions include dyspnoea among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Starlix and Reglan. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Starlix?

Starlix has active ingredients of nateglinide. It is often used in diabetes. eHealthMe is studying from 3,768 Starlix users. Check the latest studies of Starlix.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.



On Jul, 30, 2026

62 people who take Starlix and Reglan together, and have interactions are studied.

Starlix and Reglan drug interactions.

What are the common drug interactions of Starlix and Reglan, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Anxiety
  3. Atelectasis (partial or complete collapse of the lung)
  4. Colitis (inflammation of colon)
  5. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  6. Hypertension (high blood pressure)
  7. Osteonecrosis of jaw (death of bone of jaw)
  8. Pneumonia
  9. Arthralgia (joint pain)
  10. Constipation

male:

  1. Back pain
  2. Cardiomegaly (increased size of heart than normal)
  3. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  4. Chest pain
  5. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  6. Decreased appetite
  7. Dehydration (dryness resulting from the removal of water)
  8. Hypoglycaemia (deficiency of glucose in the bloodstream)
  9. Renal impairment (severely reduced kidney function)
  10. Vomiting

What are the common drug interactions of Starlix and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Acute hepatic failure
  2. Overdose

30-39:

n/a

40-49:

  1. Confusional state
  2. Abdominal pain
  3. Abscess neck (neck abscesses)
  4. Accommodation disorder
  5. Adenomyosis (presence of ectopic glandular tissue found in muscle)
  6. Altered state of consciousness (altered state of mind)
  7. Altered visual depth perception
  8. Anaemia (lack of blood)
  9. Aphasia (damage to the parts of the brain that control language)
  10. Arthralgia (joint pain)

50-59:

  1. Cardiomegaly (increased size of heart than normal)
  2. Acute myocardial infarction (acute heart attack)
  3. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  4. Discomfort
  5. Dyspnoea (difficult or laboured respiration)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Muscle spasms (muscle contraction)
  8. Pruritus (severe itching of the skin)
  9. Pyrexia (fever)
  10. Renal failure chronic (long lasting kidney dysfunction)

60+:

  1. Pain
  2. Injury
  3. Atelectasis (partial or complete collapse of the lung)
  4. Cataract (clouding of the lens inside the eye)
  5. Chest pain
  6. Colitis (inflammation of colon)
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Diarrhoea
  9. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  10. Hypertension (high blood pressure)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 15 people, 24.19%
  2. Depression: 13 people, 20.97%
  3. High Blood Pressure: 12 people, 19.35%
  4. Metastases To Bone (cancer spreads to bone): 11 people, 17.74%
  5. Breast Cancer: 11 people, 17.74%
  6. Bone Pain: 11 people, 17.74%
  7. Type 2 Diabetes: 5 people, 8.06%

* Approximation only. Some reports may have incomplete information.

Do you take Starlix and Reglan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Starlix and Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Starlix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Starlix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Reglan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nateglinide and metoclopramide hydrochloride (the active ingredients of Starlix and Reglan, respectively), and Starlix and Reglan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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