Strattera and Aleve drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Strattera (atomoxetine hydrochloride) and Aleve (naproxen sodium). Common drug interactions include rhinorrhoea among females and bone density decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Strattera and Aleve. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Strattera?

Strattera has active ingredients of atomoxetine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,324 Strattera users. Check the latest studies of Strattera.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

On Jul, 31, 2026

79 people who take Strattera and Aleve together, and have interactions are studied.

What are the common drug interactions of Strattera and Aleve, by gender? *:

female:

Rhinorrhoea (watery mucus discharge from the nose)
Therapeutic response unexpected
Ulcer
Abdominal abscess (collection of pus in abdomen)
Abdominal tenderness
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Drug hypersensitivity
Hepatic enzyme increased
Sneezing
Abdominal distension

male:

Bone density decreased
Fatigue (feeling of tiredness)
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Tinnitus (a ringing in the ears)
Urinary hesitation (difficulty in beginning the flow of urine)
Anger
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataplexy (loss of muscle tone accompanied by full conscious awareness)

What are the common drug interactions of Strattera and Aleve, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Back pain
Influenza
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Rhinorrhoea (watery mucus discharge from the nose)
Abdominal pain upper
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Blood pressure decreased

20-29:

Bone density decreased
Hip fracture
Arthralgia (joint pain)
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Ovarian cyst (fluid filled sac of the ovary)
Nasopharyngitis (inflammation of the nasopharynx)

30-39:

Chronic kidney disease
Nausea (feeling of having an urge to vomit)
Pancreatitis (inflammation of pancreas)
Renal failure (kidney dysfunction)
Therapeutic response unexpected
Ulcer
Alopecia (absence of hair from areas of the body)
Dysmenorrhoea (painful menstruation)
Dysuria (painful or difficult urination)
Micturition disorder (disease of passing urine)

40-49:

Nausea (feeling of having an urge to vomit)
Abdominal abscess (collection of pus in abdomen)
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Drug hypersensitivity
Vomiting
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Heart rate increased
Insomnia (sleeplessness)
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
Vision blurred

50-59:

Fatigue (feeling of tiredness)
Apathy
Asthenia (weakness)
Deafness
Increased appetite
Influenza like illness
Lethargy (tiredness)
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Tinnitus (a ringing in the ears)

60+:

Fatigue (feeling of tiredness)
Abnormal faeces (abnormal stool)
Feeling jittery
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Hypnagogic hallucination
Libido decreased (loss of interest in sex)
Muscle spasms (muscle contraction)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Restlessness (not able to rest)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 34 people, 43.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 17.72%
Drowsiness: 12 people, 15.19%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 6.33%
Combined Immunodeficiency: 5 people, 6.33%

* Approximation only. Some reports may have incomplete information.

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