Strattera and Sudafed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Strattera (atomoxetine hydrochloride) and Sudafed (pseudoephedrine hydrochloride). Common drug interactions include eye swelling among females and paraesthesia among males.

The phase IV clinical study analyzes what interactions people have when they take Strattera and Sudafed. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Strattera?

Strattera has active ingredients of atomoxetine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,324 Strattera users. Check the latest studies of Strattera.

What is Sudafed?

Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion. eHealthMe is studying from 12,944 Sudafed users. Check the latest studies of Sudafed.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

43 people who take Strattera and Sudafed together, and have interactions are studied.

Strattera and Sudafed drug interactions.

What are the common drug interactions of Strattera and Sudafed, by gender? *:

female:

Eye swelling
Feeling hot and cold
Furuncle (infection of the hair follicle)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Heart rate irregular
Hypertension (high blood pressure)
Infusion related reaction
Injury
Insomnia (sleeplessness)

male:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Decreased appetite
Hypotension (abnormally low blood pressure)
Peripheral coldness
Vertigo
Erectile dysfunction
Prostatic pain
Dysuria (painful or difficult urination)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Constipation

What are the common drug interactions of Strattera and Sudafed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abnormal behaviour
Aggression
Excitability
Nasopharyngitis (inflammation of the nasopharynx)

10-19:

Anger
Crying
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Loss of consciousness
Micturition urgency (urgency to pass the urine)
Urinary retention (the inability to completely or partially empty the bladder)

20-29:

Oral herpes (viral infection of mouth)
Oropharyngeal pain
Pain
Pain in extremity
Photosensitivity reaction
Piloerection (goose bumps)
Skin lesion
Vomiting
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Balance disorder

30-39:

Abdominal discomfort
Depressed mood
Blood glucagon increased
Crying
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Electric shock
Irritability
Mood swings (an extreme or rapid change in mood)
Nervousness
Pruritus (severe itching of the skin)

40-49:

Drug ineffective
Asthenia (weakness)
Blood hiv rna increased
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Dizziness
Dry throat
Exercise capacity decreased
Fatigue (feeling of tiredness)
Feeling hot

50-59:

Oral surgery
Sinus disorder (disease of sinus)
Sinusitis (inflammation of sinus)
Skin infection
Upper respiratory tract infection
Anxiety
Calcinosis (calcium deposits in any soft tissue)
Chest pain
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Heart rate irregular

60+:

Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Tendon rupture (tear of tendon)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 23.26%
Depression: 7 people, 16.28%
Immunodeficiency Common Variable: 5 people, 11.63%
Stress And Anxiety: 4 people, 9.30%
Myositis (inflammation of the muscles): 4 people, 9.30%
Hypersensitivity: 4 people, 9.30%
Cushing's Syndrome (obesity, a rounded face, increased fat): 4 people, 9.30%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 6.98%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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