Sublimaze and Humalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sublimaze (fentanyl citrate) and Humalog (insulin lispro recombinant). Common drug interactions include joint dislocation among females and abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Sublimaze and Humalog. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Sublimaze?

Sublimaze has active ingredients of fentanyl citrate. eHealthMe is studying from 560 Sublimaze users. Check the latest studies of Sublimaze.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

On Jul, 21, 2026

42 people who take Sublimaze and Humalog together, and have interactions are studied.

Sublimaze and Humalog drug interactions.

What are the common drug interactions of Sublimaze and Humalog, by gender? *:

female:

Joint dislocation (a joint position is changed from normal position)
Joint effusion (presence of extra fluid in joint covering)
Joint swelling
Multiple myeloma (cancer of the plasma cells)
Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
Oedema peripheral (superficial swelling)
Osteolysis (dissolution of bone)
Spinal compression fracture (fracture due to spinal compression on bone)
Synovial cyst (cyst of joint filled with synovial fluid)
Weight decreased

male:

Abscess (pus)
Blood creatinine increased
Cellulitis (infection under the skin)
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Gas gangrene (bacterial infection that produces gas within tissues)
Groin abscess (pus in groin)
Groin pain
Large intestine perforation (hole in large intestine)
Scrotal cyst (cyst of scrotum)
Scrotal pain

What are the common drug interactions of Sublimaze and Humalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Acute hepatic failure
Arthralgia (joint pain)
Aspartate aminotransferase increased
Decreased appetite
Encephalopathy (functioning of the brain is affected by some agent or condition)
Epistaxis (bleed from the nose)
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypercalcaemia (elevated calcium (ca+) level in the blood)

30-39:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

40-49:

Abscess (pus)
Blood creatinine increased
Exostosis (formation of new bone on the surface of a bone)
International normalised ratio increased
Localised infection (infection at the single location)
Muscular weakness (muscle weakness)
Post procedural haemorrhage (post procedural bleeding)
Skin ulcer
Cellulitis (infection under the skin)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

50-59:

Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abscess limb (limb infection)
Gas gangrene (bacterial infection that produces gas within tissues)
Groin abscess (pus in groin)
Groin pain
Scrotal cyst (cyst of scrotum)
Scrotal pain
Scrotal swelling
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Contusion (a type of hematoma of tissue in which capillaries)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Disability
Dizziness
Ear infection
Excoriation (to tear or wear off the skin of)
Fall

What are the existing conditions these people have? *

Pain: 11 people, 26.19%
Type 2 Diabetes: 8 people, 19.05%
High Blood Pressure: 7 people, 16.67%
Hypotension (abnormally low blood pressure): 6 people, 14.29%
Weight Decreased: 6 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.90%
Constipation: 5 people, 11.90%
Nausea (feeling of having an urge to vomit): 4 people, 9.52%
Stress And Anxiety: 4 people, 9.52%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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