Subutex and Proair hfa drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Subutex (buprenorphine hydrochloride) and Proair hfa (albuterol sulfate). Common drug interactions include drug withdrawal syndrome neonatal among females and amnesia among males.
The phase IV clinical study analyzes what interactions people have when they take Subutex and Proair hfa. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Subutex?
Subutex has active ingredients of buprenorphine hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 8,763 Subutex users. Check the latest studies of Subutex.
What is Proair hfa?
Proair hfa has active ingredients of albuterol sulfate. It is often used in asthma. eHealthMe is studying from 53,227 Proair hfa users. Check the latest studies of Proair hfa.
26 people who take Subutex and Proair hfa together, and have interactions are studied.

What are the common drug interactions of Subutex and Proair Hfa, by gender? *:
female:
- Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
- Amniotic infection syndrome of blane
- Ascites (accumulation of fluid in the abdominal cavity)
- Drug exposure during pregnancy
- Drug screen positive
- Hyperkalaemia (damage to or disease of the kidney)
- Hypoglycaemia neonatal (deficiency of glucose in the bloodstream in neonatal)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Klinefelter's syndrome (a chromosomal abnormality (xxy)weaker muscles and reduced strength)
male:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chest pain
- Confusional state
- Fatigue (feeling of tiredness)
- Memory impairment
- Migraine (headache)
- Muscle spasms (muscle contraction)
- Rib fracture
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
What are the common drug interactions of Subutex and Proair Hfa, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Drug screen positive
- Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
30-39:
- Drug exposure during pregnancy
- Postpartum haemorrhage (bleeding in woman after she has given birth)
40-49:
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Night sweats (sweating in night)
- Vomiting
- Cardiovascular disorder (heart diseases)
- Blindness
- Chronic kidney disease
- Drug ineffective
- Eye infection
- Renal injury (kidney injury)
50-59:
n/a
60+:
- Amniotic infection syndrome of blane
- Ascites (accumulation of fluid in the abdominal cavity)
- Subarachnoid haemorrhage neonatal (blood leaks into the space between two membranes that surround the brain in newborn)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Infection
- Mouth ulceration (mouth ulcers)
- Nail disorder (disease of nail)
- Pruritus (severe itching of the skin)
- Skin disorder (skin disease)
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 73.08%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 18 people, 69.23%
- Quit Smoking: 3 people, 11.54%
- Drug Dependence: 3 people, 11.54%
- Insomnia (sleeplessness): 2 people, 7.69%
- High Blood Cholesterol: 2 people, 7.69%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 2 people, 7.69%
- Drowsiness: 2 people, 7.69%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Subutex and Proair hfa?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Subutex (8,763 reports)
- Proair hfa (53,227 reports)
Browse all drug interactions of Subutex and Proair hfa:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Subutex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Proair hfa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Subutex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Proair hfa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on buprenorphine hydrochloride and albuterol sulfate (the active ingredients of Subutex and Proair hfa, respectively), and Subutex and Proair hfa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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