Sucralfate and Actigall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sucralfate (sucralfate) and Actigall (ursodiol). Common drug interactions include nausea among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Sucralfate and Actigall. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Sucralfate?

Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

16 people who take Sucralfate and Actigall together, and have interactions are studied.

Sucralfate and Actigall drug interactions.

What are the common drug interactions of Sucralfate and Actigall, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Weight increased
Abdominal adhesions (inflammation of abdomen)
Biliary cirrhosis (biliary cirrhosis occurs due to obstruction to the flow of bile through bile ducts either within the liver or outside the liver)
Cerebral haematoma (collection of blood in brain)
Cerebral haemorrhage (bleeding within the brain)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Coagulopathy (blood's ability to clot is impaired)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

male:

Dehydration (dryness resulting from the removal of water)
Dysphagia (a condition in which swallowing is difficult or painful)
Chronic kidney disease
Colitis haemorrhagic (bleeding diarrhoea due to infection of colon)
Cytomegalovirus infection
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Fungal infection

What are the common drug interactions of Sucralfate and Actigall, by age (0-1 to 60+)? *:

0-1:

Abdominal adhesions (inflammation of abdomen)
Biliary cirrhosis (biliary cirrhosis occurs due to obstruction to the flow of bile through bile ducts either within the liver or outside the liver)
Cerebral haematoma (collection of blood in brain)
Cerebral haemorrhage (bleeding within the brain)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Coagulopathy (blood's ability to clot is impaired)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Hypersensitivity
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

2-9:

n/a

10-19:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Pneumonia

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Dysphagia (a condition in which swallowing is difficult or painful)
Oesophageal ulcer (ulcer of oesophagus)
Oesophagitis (inflammation of oesophagus)
Blood alkaline phosphatase nos increased
Blood amylase decreased
Dehydration (dryness resulting from the removal of water)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Haematocrit decreased
Haemoglobin abnormal
International normalised ratio decreased

60+:

Ascites (accumulation of fluid in the abdominal cavity)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Fungal infection
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Hepatic function abnormal
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Nervous System Disorder (a general class of medical conditions affecting the nervous system): 6 people, 37.50%
Neoplasm Malignant (cancer tumour): 6 people, 37.50%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 12.50%
Toxic Neuropathy (nerve damage caused by toxic (harmful) substances): 2 people, 12.50%
Gastric Ulcer (stomach ulcer): 2 people, 12.50%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.25%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 6.25%
Cough: 1 person, 6.25%
Cystic Fibrosis (disease of the secretary glands): 1 person, 6.25%
Delusion (a false belief or opinion): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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