Sucralfate and Atarax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sucralfate (sucralfate) and Atarax (hydroxyzine hydrochloride). Common drug interactions include haemorrhoids among females and cytolytic hepatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Sucralfate and Atarax. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Sucralfate?

Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.



On Jul, 11, 2026

84 people who take Sucralfate and Atarax together, and have interactions are studied.

Sucralfate and Atarax drug interactions.

What are the common drug interactions of Sucralfate and Atarax, by gender? *:

female:

  1. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  2. Acne (skin problems that cause pimples)
  3. Blood glucose increased
  4. Constipation
  5. Dermatitis allergic (inflammation of the skin due allergic reaction)
  6. Dyslipidaemia (abnormal amount of lipids)
  7. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  8. Joint swelling
  9. Lymphadenopathy (disease or enlargement of lymph nodes)
  10. Multiple allergies (allergy to multiple agents)

male:

  1. Cytolytic hepatitis (dissolution or destruction of a liver cell)
  2. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  3. Brain contusion (a form of traumatic brain injury)
  4. Chills (felling of cold)
  5. Depression
  6. Dyspnoea (difficult or laboured respiration)
  7. Fall
  8. Inappropriate antidiuretic hormone secretion
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Pain

What are the common drug interactions of Sucralfate and Atarax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal pain upper
  2. Decreased appetite
  3. Diarrhoea
  4. Headache (pain in head)
  5. Nausea (feeling of having an urge to vomit)
  6. Petechiae (a small red or purple spot caused by bleeding into the skin)
  7. Abnormal behaviour
  8. Blood sodium decreased
  9. Platelet count increased
  10. Post procedural haemorrhage (post procedural bleeding)

20-29:

  1. Depression
  2. Discomfort
  3. Drug resistance (reduction in effectiveness of a drug)
  4. Emotional distress
  5. Headache (pain in head)
  6. Migraine (headache)
  7. Mood swings (an extreme or rapid change in mood)
  8. Nausea (feeling of having an urge to vomit)
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Night sweats (sweating in night)

30-39:

  1. Abdominal pain
  2. Acne (skin problems that cause pimples)
  3. Anaemia (lack of blood)
  4. Arthralgia (joint pain)
  5. Blood cholesterol increased
  6. Blood glucose increased
  7. Blood pressure increased
  8. Blood triglycerides increased
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Contusion (a type of hematoma of tissue in which capillaries)

40-49:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Hypokalaemia (low potassium)
  3. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  4. Pneumonia
  5. Arthralgia (joint pain)
  6. Ascites (accumulation of fluid in the abdominal cavity)
  7. Aspartate aminotransferase increased
  8. Atelectasis (partial or complete collapse of the lung)
  9. Blood lactate dehydrogenase increased
  10. Blood phosphorus increased

50-59:

  1. Red blood cell count decreased
  2. Blood lactate dehydrogenase increased
  3. Hairy cell leukaemia (a type of blood cancer)
  4. Headache (pain in head)
  5. Hypertension (high blood pressure)
  6. Nausea (feeling of having an urge to vomit)
  7. Abdominal discomfort
  8. Abdominal pain
  9. Abdominal pain upper
  10. Acute myocardial infarction (acute heart attack)

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Cellulitis (infection under the skin)
  3. Hypoglycaemia (deficiency of glucose in the bloodstream)
  4. Inappropriate antidiuretic hormone secretion
  5. Muscular weakness (muscle weakness)
  6. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  7. Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
  8. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  9. Erythema (redness of the skin)
  10. General physical health deterioration (weak health status)

What are the existing conditions these people have? *

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 14 people, 16.67%
  2. Nausea And Vomiting: 8 people, 9.52%
  3. Nausea (feeling of having an urge to vomit): 8 people, 9.52%
  4. Itching: 7 people, 8.33%
  5. Pain: 6 people, 7.14%
  6. Pneumonia Legionella (pneumonia caused by the bacteria legionella): 5 people, 5.95%
  7. Migraine (headache): 5 people, 5.95%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sucralfate and Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sucralfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sucralfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atarax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sucralfate and hydroxyzine hydrochloride (the active ingredients of Sucralfate and Atarax, respectively), and Sucralfate and Atarax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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