Sucralfate and Hetlioz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sucralfate (sucralfate) and Hetlioz (tasimelteon). Common drug interactions include somnolence among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Sucralfate and Hetlioz. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Sucralfate?

Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.

What is Hetlioz?

Hetlioz has active ingredients of tasimelteon. eHealthMe is studying from 7,418 Hetlioz users. Check the latest studies of Hetlioz.



On Aug, 10, 2026

16 people who take Sucralfate and Hetlioz together, and have interactions are studied.

Sucralfate and Hetlioz drug interactions.

What are the common drug interactions of Sucralfate and Hetlioz, by gender? *:

female:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Insomnia (sleeplessness)
  3. Headache (pain in head)
  4. Pneumonia
  5. Respiratory distress (difficulty in breathing)
  6. Abdominal pain upper
  7. Asthenia (weakness)
  8. Colour blindness acquired (development of colour vision disability due to damage to eye)
  9. Discomfort
  10. Fall

male:

  1. Decreased appetite
  2. Drug ineffective
  3. Insomnia (sleeplessness)
  4. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  5. Stress
  6. Sedation
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Adverse drug reaction
  10. Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)

What are the common drug interactions of Sucralfate and Hetlioz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Adverse drug reaction
  2. Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
  3. Constipation
  4. Decreased activity
  5. Drug ineffective
  6. Eating disorder
  7. Insomnia (sleeplessness)
  8. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  9. Stress
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

  1. Insomnia (sleeplessness)
  2. Pneumonia
  3. Respiratory distress (difficulty in breathing)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

  1. Headache (pain in head)
  2. Colour blindness acquired (development of colour vision disability due to damage to eye)
  3. Discomfort
  4. Nausea (feeling of having an urge to vomit)
  5. Weight increased

What are the existing conditions these people have? *

  1. Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 3 people, 18.75%
  2. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 12.50%
  3. Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 2 people, 12.50%
  4. Blindness: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Sucralfate and Hetlioz?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sucralfate and Hetlioz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sucralfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hetlioz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sucralfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hetlioz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sucralfate and tasimelteon (the active ingredients of Sucralfate and Hetlioz, respectively), and Sucralfate and Hetlioz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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