Sudafed and Byetta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sudafed (pseudoephedrine hydrochloride) and Byetta (exenatide synthetic). Common drug interactions include injection site mass among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Sudafed and Byetta. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Sudafed?

Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion. eHealthMe is studying from 12,944 Sudafed users. Check the latest studies of Sudafed.

What is Byetta?

Byetta has active ingredients of exenatide synthetic. It is often used in diabetes. eHealthMe is studying from 60,818 Byetta users. Check the latest studies of Byetta.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

20 people who take Sudafed and Byetta together, and have interactions are studied.

What are the common drug interactions of Sudafed and Byetta, by gender? *:

female:

Injection site mass
Injection site pain
Blood glucose decreased
Coma (state of unconsciousness lasting more than six hours)
Nasopharyngitis (inflammation of the nasopharynx)
Thrombosis (formation of a blood clot inside a blood vessel)
Weight decreased
Acute respiratory distress syndrome
Asthenia (weakness)
Blood glucose increased

male:

Weight decreased
Blood glucose decreased
Sleep disorder
Tremor (trembling or shaking movements in one or more parts of your body)
Fall
Pleural effusion (water on the lungs)
Drug hypersensitivity
Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Injection site pruritus (severe itching at injection site)
Blood glucose increased

What are the common drug interactions of Sudafed and Byetta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood glucose decreased
Weight decreased
Acute respiratory distress syndrome
Asthenia (weakness)
Blood glucose increased
Coma (state of unconsciousness lasting more than six hours)
Depression
Fall
Fatigue (feeling of tiredness)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)

50-59:

Weight decreased
Tremor (trembling or shaking movements in one or more parts of your body)
Drug hypersensitivity
Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Injection site pruritus (severe itching at injection site)
Blood glucose decreased
Blood pressure increased
Cold sweat
Cough
Decreased appetite

60+:

Thrombosis (formation of a blood clot inside a blood vessel)
Injection site mass
Shock hypoglycaemic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to less sugar in body)
Tendon rupture (tear of tendon)
Injection site pain
Coma (state of unconsciousness lasting more than six hours)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Injection site erythema (redness at injection site)
Injection site reaction
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Type 2 Diabetes: 11 people, 55.00%
High Blood Pressure: 3 people, 15.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 10.00%
Heart Rate Irregular: 2 people, 10.00%
Hypersensitivity: 2 people, 10.00%
Asthma: 2 people, 10.00%
Thyroid Diseases: 2 people, 10.00%
Multiple Allergies (allergy to multiple agents): 1 person, 5.00%
Memory Loss: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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