Sudafed and Bystolic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sudafed (pseudoephedrine hydrochloride) and Bystolic (nebivolol hydrochloride). Common drug interactions include renal impairment among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Sudafed and Bystolic. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Sudafed?

Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion. eHealthMe is studying from 12,944 Sudafed users. Check the latest studies of Sudafed.

What is Bystolic?

Bystolic has active ingredients of nebivolol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 20,662 Bystolic users. Check the latest studies of Bystolic.

On Jul, 11, 2026

33 people who take Sudafed and Bystolic together, and have interactions are studied.

What are the common drug interactions of Sudafed and Bystolic, by gender? *:

female:

Renal impairment (severely reduced kidney function)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Scab (a hard coating on the skin formed during the wound healing)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
Tooth infection
Upper respiratory tract infection
Vision blurred
Visual field defect
Visual impairment

male:

Pain
Arthralgia (joint pain)
Hospitalisation
Lipoma excision
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Pneumonia
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Stress

What are the common drug interactions of Sudafed and Bystolic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Headache (pain in head)

50-59:

Infusion site erythema (reddening of the skin at infusion site)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Infusion site irritation
Infusion site swelling
Muscle spasms (muscle contraction)
Sinusitis (inflammation of sinus)
Drug administration error
Eye infection
Headache (pain in head)
Arthralgia (joint pain)

60+:

Nausea (feeling of having an urge to vomit)
Pneumonia
Diarrhoea
Dry eye (lack of adequate tears)
Dry mouth
Dry skin
Dysphagia (a condition in which swallowing is difficult or painful)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fall
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Muscle Spasms (muscle contraction): 5 people, 15.15%
High Blood Cholesterol: 5 people, 15.15%
Sleep Disorder: 4 people, 12.12%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 9.09%
Pain: 3 people, 9.09%
Nausea (feeling of having an urge to vomit): 3 people, 9.09%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 9.09%
Hypersensitivity: 3 people, 9.09%
Viral Upper Respiratory Tract Infection: 2 people, 6.06%
Asthma: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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